

Cruise itinerary
7-Night Europe Cruise from Civitavecchia
7 nights · Europe · 8 ports of call
7-night Europe cruise aboard Oceania Sirena, departing Civitavecchia and calling at Naples, Messina, Valletta, At Sea, Piraeus and Lesbos and 1 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 7 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Civitavecchia
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2

Naples
Arrive 07:00 · Depart 18:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day3

Messina
Arrive 07:00 · Depart 19:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day4

Valletta
Arrive 07:00 · Depart 19:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day5
At Sea
- Day6

Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day7
Lesbos
Arrive 07:00 · Depart 14:00
- Day8

Istanbul
Arrive 07:00 · Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 5 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
7-Night Europe Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 7-night Europe cruise calls at Civitavecchia, Naples, Messina, Valletta, At Sea, Piraeus, Lesbos and Istanbul.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Istanbul.
How long is this cruise?
7 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 5 Nov 2026. A NestCruise advisor can confirm current availability.