

Cruise itinerary
21-Night South America Cruise from Rio de Janeiro
21 nights · South America · 10 ports of call
21-night South America cruise aboard Oceania Sirena, departing Rio de Janeiro and calling at Maceió, Santarém, Boca da Valeria, Manaus, Parintins and Bridgetown and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 21 nights
- Region
- South America
- Departs
- Rio de Janeiro
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Rio de Janeiro
Depart 17:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day2At sea
- Day3At sea
- Day4

Maceió
Arrive 07:00 · Depart 17:00
The capital of Alagoas on Brazil's north-east coast, fringed by white sand and warm reef-protected lagoons. Pajuçara and Ponta Verde beaches draw swimmers, and jangada rafts carry visitors out to the natural tidal pools offshore.
- Pajuçara beach
- Natural pools
- Jangada rafts
- Day5At sea
- Day6At sea
- Day7At sea
- Day8At sea
- Day9

Santarém
Arrive 08:00 · Depart 17:00
- Day10
Boca da Valeria
Arrive 07:00 · Depart 14:00
- Day11

Manaus
Arrive 09:00 · Depart 17:00
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day12At sea
- Day13

Parintins
Arrive 10:00 · Depart 18:00
- Day14At sea
- Day15At sea
- Day16At sea
- Day17

Bridgetown
Arrive 09:00 · Depart 17:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day18

Pointe-à-Pitre
Arrive 09:00 · Depart 17:00
The main town of Guadeloupe, a French overseas region in the eastern Caribbean shaped like a butterfly. It sits between the two wings of the island, with a covered spice market, Creole cooking and the volcano of La Soufrière to the south.
- Spice market
- La Soufrière
- Memorial ACTe
- Day19

Tortola
Arrive 10:00 · Depart 17:00
The main island of the British Virgin Islands, where steep green hills drop to a yacht-filled harbour at Road Town. It is a noted sailing base in the Caribbean, with quiet bays such as Cane Garden and ferries out to neighbouring Virgin Gorda.
- Road Town
- Cane Garden Bay
- Sailing charters
- Day20At sea
- Day21At sea
- Day22

Miami, Florida
Arrive 08:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 18 Feb 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night South America Cruise from Rio de Janeiro FAQ
Which ports does this cruise visit?
This 21-night South America cruise calls at Rio de Janeiro, Maceió, Santarém, Boca da Valeria, Manaus, Parintins, Bridgetown, Pointe-à-Pitre, Tortola and Miami, Florida.
How many days are spent at sea?
12 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Rio de Janeiro and ends in Miami, Florida.
How long is this cruise?
21 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 18 Feb 2028. A NestCruise advisor can confirm current availability.