Cruise itinerary
19-Night Mediterranean Cruise from Civitavecchia
19 nights · Mediterranean · 19 ports of call
19-night Mediterranean cruise aboard Oceania Sirena, departing Civitavecchia and calling at Salerno, Palermo, Catania, Zakynthos, Gythion and Mykonos and 12 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 19 nights
- Region
- Mediterranean
- Departs
- Civitavecchia
- Returns
- Venice
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Civitavecchia
Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2
Salerno
Arrive 07:00 · Depart 17:00
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day3
Palermo
Arrive 07:00 · Depart 17:00
The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
- Cappella Palatina
- Ballarò market
- Monreale mosaics
- Day4
Catania
Arrive 07:00 · Depart 16:00
A port city on the east coast of Sicily, built in dark volcanic stone beneath Mount Etna, Europe's most active volcano. Its baroque centre, rebuilt after earthquakes, is known for the elephant fountain, a fish market, and Etna excursions inland.
- Mount Etna
- Baroque centre
- Fish market
- Day5
Zakynthos
Arrive 13:00 · Depart 22:00
- Day6
Gythion
Arrive 09:00 · Depart 17:00
- Day7
Mykonos
Arrive 07:00 · Depart 19:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day8
Vólos
Arrive 08:00 · Depart 18:00
A coastal city on the Pagasetic Gulf in central Greece, ringed by the wooded slopes of Mount Pelion. A seafront promenade lines the waterfront, and the surrounding mountain villages and beaches are reached by a scenic road up the peninsula.
- Pelion villages
- Seafront promenade
- Tsipouro tavernas
- Day9
Çanakkale
Arrive 08:00 · Depart 18:00
A Turkish port at the narrowest point of the Dardanelles strait, between the Aegean and the Sea of Marmara. It is the gateway to the ruins of ancient Troy and to the Gallipoli battlefields and war memorials across the water on the peninsula.
- Ancient Troy
- Gallipoli battlefields
- Dardanelles strait
- Day10
Istanbul
Arrive 07:00 · Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11
Lesbos
Arrive 09:00 · Depart 19:00
- Day12
Kusadasi
Arrive 08:00 · Depart 18:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day13
Soúda, Crete
Arrive 09:00 · Depart 17:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day14
Kefalonia (Argostoli), Greece
Arrive 10:00 · Depart 19:00
- Day15
Durres
Arrive 10:00 · Depart 18:00
- Day16
Kotor
Arrive 07:00 · Depart 19:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day17
Korčula
Arrive 07:00 · Depart 17:00
A walled medieval town on its own island off the Dalmatian coast of Croatia, in the Adriatic. Stone houses cluster within the ramparts in a herringbone street plan, and the island's interior of vineyards and olive groves produces well-regarded white wines.
- town walls
- Marco Polo house
- island vineyards
- Day18
Ravenna
Arrive 10:00 · Depart 20:00
A historic city near the Adriatic coast of northern Italy, once the capital of the late Roman and Byzantine West. It is celebrated for early Christian mosaics in its churches and mausoleums, several of them UNESCO World Heritage sites.
- Byzantine mosaics
- San Vitale basilica
- Dante's tomb
- Day19
Venice
Arrive 07:00 · Depart 07:00
A city built across more than a hundred islands in a lagoon on the Adriatic, threaded by canals instead of streets. Venice is known for St. Mark's Basilica and its piazza, the Grand Canal and Rialto Bridge, and the glass workshops of Murano nearby.
- St. Mark's Square
- Grand Canal
- Rialto Bridge
- Day20
Venice
A city built across more than a hundred islands in a lagoon on the Adriatic, threaded by canals instead of streets. Venice is known for St. Mark's Basilica and its piazza, the Grand Canal and Rialto Bridge, and the glass workshops of Murano nearby.
- St. Mark's Square
- Grand Canal
- Rialto Bridge
Upcoming departures
- 19 Jul 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
19-Night Mediterranean Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 19-night Mediterranean cruise calls at Civitavecchia, Salerno, Palermo, Catania, Zakynthos, Gythion, Mykonos, Vólos, Çanakkale, Istanbul, Lesbos, Kusadasi, Soúda, Crete, Kefalonia (Argostoli), Greece, Durres, Kotor, Korčula, Ravenna and Venice.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Venice.
How long is this cruise?
19 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 19 Jul 2027. A NestCruise advisor can confirm current availability.