Cruise itinerary
14-Night Europe Cruise from Istanbul
14 nights · Europe · 13 ports of call
14-night Europe cruise aboard Oceania Sirena, departing Istanbul and calling at Izmir, Santorini, Rhodes, Heraklion (Iraklion), Crete, At Sea and Dubrovnik and 6 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 14 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Istanbul
- Returns
- Civitavecchia
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Istanbul
Arrive 07:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day2
Istanbul
Depart 14:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day3
Izmir
Arrive 10:00 · Depart 19:00
- Day4
Santorini
Arrive 10:00 · Depart 21:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day5
Rhodes
Arrive 08:00 · Depart 17:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day6
Heraklion (Iraklion), Crete
Arrive 07:00 · Depart 17:00
The largest city on Crete and the island's main port, in Greece. A Venetian harbour and fortress front the town, while the Bronze Age palace of Knossos and the Heraklion Archaeological Museum's Minoan treasures lie close by.
- Palace of Knossos
- Venetian harbour
- Archaeological Museum
- Day7
At Sea
- Day8
Dubrovnik
Arrive 09:00 · Depart 19:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day9
Kotor
Arrive 07:00 · Depart 17:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day10
Sarandë
Arrive 09:00 · Depart 18:00
A coastal town in southern Albania on the Ionian Sea, facing the Greek island of Corfu across a narrow strait. Its curved bay and beaches anchor the town, and the ancient ruins of Butrint lie a short way down the coast.
- Butrint ruins
- Ionian beaches
- Lëkurësi Castle
- Day11
Katakolon
Arrive 10:00 · Depart 20:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day12
At Sea
- Day13
Taormina
Arrive 09:00 · Depart 19:00
A hilltop town on Sicily's east coast, perched above the Ionian Sea with Mount Etna on the horizon. Its ancient Greek theatre, medieval lanes and gardens look down on the coast, with the beaches of Giardini Naxos and Isola Bella below.
- Greek Theatre
- Isola Bella
- Mount Etna views
- Day14
Sorrento
Arrive 09:00 · Depart 19:00
A clifftop town on Italy's Bay of Naples, perched above the sea facing Vesuvius. Sorrento is known for its lemon groves and limoncello, a tangle of narrow shopping lanes, and its role as a base for Capri, Pompeii, and the Amalfi Coast.
- Marina Grande
- Lemon groves
- Piazza Tasso
- Day15
Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
Upcoming departures
- 27 Aug 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
14-Night Europe Cruise from Istanbul FAQ
Which ports does this cruise visit?
This 14-night Europe cruise calls at Istanbul, Izmir, Santorini, Rhodes, Heraklion (Iraklion), Crete, At Sea, Dubrovnik, Kotor, Sarandë, Katakolon, Taormina, Sorrento and Civitavecchia.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Istanbul and ends in Civitavecchia.
How long is this cruise?
14 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 27 Aug 2026. A NestCruise advisor can confirm current availability.