Cruise itinerary
14-Night Americas Cruise from Miami, Florida
14 nights · Americas · 11 ports of call
14-night Americas cruise aboard Oceania Sirena, departing Miami, Florida and calling at At Sea, Georgetown, Grand Cayman, Ocho Rios, Santa Marta, Cartagena and Colón and 4 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 14 nights
- Region
- Americas · South America
- Departs
- Miami, Florida
- Returns
- Callao
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2
At Sea
- Day3
Georgetown, Grand Cayman
Arrive 11:00 · Depart 18:00
Grand Cayman's capital and the main port of the Cayman Islands, set on the calm western shore. Cruise ships tender into the harbour beside Seven Mile Beach, with Stingray City sandbars and Caribbean reef diving a short boat ride away.
- Seven Mile Beach
- Stingray City
- Seven Mile reefs
- Day4
Ocho Rios
Arrive 11:00 · Depart 20:00
A resort town on Jamaica's north coast, set among green hills and a string of beaches. The terraced cascades of Dunn's River Falls are the headline attraction, with botanical gardens, river tubing and reggae-filled markets close to the cruise pier.
- Dunn's River Falls
- Resort beaches
- Botanical gardens
- Day5
At Sea
- Day6
Santa Marta
Arrive 07:00 · Depart 17:00
- Day7
Cartagena
Arrive 07:00 · Depart 13:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day8
Colón
Arrive 08:00 · Depart 20:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day9
Panama Canal Transit
Arrive 06:00 · Depart 18:00
- Day10
At Sea
- Day11
Manta
Arrive 07:00 · Depart 17:00
- Day12
At Sea
- Day13
Salaverry
Arrive 07:00 · Depart 16:00
- Day14
Callao
Arrive 11:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day15
Callao
Arrive 07:00 · Depart 17:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
Upcoming departures
- 5 Jan 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
14-Night Americas Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 14-night Americas cruise calls at Miami, Florida, At Sea, Georgetown, Grand Cayman, Ocho Rios, Santa Marta, Cartagena, Colón, Panama Canal Transit, Manta, Salaverry and Callao.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Callao.
How long is this cruise?
14 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 5 Jan 2028. A NestCruise advisor can confirm current availability.