Cruise itinerary
10-Night Europe Cruise from Istanbul
10 nights · Europe · 11 ports of call
10-night Europe cruise aboard Oceania Sirena, departing Istanbul and calling at Lesbos, Kavala, Thessaloníki, Mykonos, Santorini and Agios Nikólaos, Kríti and 4 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 10 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Istanbul
- Returns
- Civitavecchia
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Istanbul
Arrive 07:00 · Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day2
Lesbos
Arrive 10:00 · Depart 18:00
- Day3
Kavala
Arrive 12:00 · Depart 20:00
- Day4
Thessaloníki
Arrive 08:00 · Depart 17:00
Greece's second city, a port on the Thermaic Gulf in the north with a long Byzantine and Ottoman past. The seafront White Tower, Roman-era Rotunda and Arch of Galerius, and a celebrated food scene of mezedes mark the waterfront.
- White Tower
- Rotunda
- Roman Forum
- Day5
Mykonos
Arrive 09:00 · Depart 18:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day6
Santorini
Arrive 09:00 · Depart 19:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day7
Agios Nikólaos, Kríti
Arrive 07:00 · Depart 14:00
A resort town on the eastern coast of Crete, built around the small saltwater Lake Voulismeni at the edge of the harbour. It looks out over the Gulf of Mirabello toward Spinalonga, the former Venetian fortress and leper colony on its islet.
- Lake Voulismeni
- Spinalonga island
- Mirabello Gulf
- Day8
Katakolon
Arrive 10:00 · Depart 17:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day9
Taormina
Arrive 11:00 · Depart 20:00
A hilltop town on Sicily's east coast, perched above the Ionian Sea with Mount Etna on the horizon. Its ancient Greek theatre, medieval lanes and gardens look down on the coast, with the beaches of Giardini Naxos and Isola Bella below.
- Greek Theatre
- Isola Bella
- Mount Etna views
- Day10
Amalfi
Arrive 09:00 · Depart 17:00
A cliff-clinging town on Italy's Amalfi Coast, once a powerful maritime republic. Its tiered houses rise from a small harbour to the striped facade of the Cathedral of St. Andrew, with lemon terraces and the scenic coast road threading along the shore.
- Amalfi Cathedral
- Lemon terraces
- Coast road drive
- Day11
Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
Upcoming departures
- 9 Jul 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Europe Cruise from Istanbul FAQ
Which ports does this cruise visit?
This 10-night Europe cruise calls at Istanbul, Lesbos, Kavala, Thessaloníki, Mykonos, Santorini, Agios Nikólaos, Kríti, Katakolon, Taormina, Amalfi and Civitavecchia.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Istanbul and ends in Civitavecchia.
How long is this cruise?
10 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 9 Jul 2027. A NestCruise advisor can confirm current availability.