

Cruise itinerary
10-Night Mediterranean Cruise from Venice
10 nights · Mediterranean · 10 ports of call
10-night Mediterranean cruise aboard Oceania Sirena, departing Venice and calling at Koper, Rijeka, Dubrovnik, Sarandë, Heraklion (Iraklion), Crete and Piraeus and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 10 nights
- Region
- Mediterranean
- Departs
- Venice
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Venice
Depart 17:00
A city built across more than a hundred islands in a lagoon on the Adriatic, threaded by canals instead of streets. Venice is known for St. Mark's Basilica and its piazza, the Grand Canal and Rialto Bridge, and the glass workshops of Murano nearby.
- St. Mark's Square
- Grand Canal
- Rialto Bridge
- Day2

Koper
Arrive 07:00 · Depart 17:00
Slovenia's main port, a compact medieval town on the Adriatic with strong Venetian roots. Its Tito Square and bell tower recall centuries under Venice, and it sits within easy reach of Ljubljana, the Postojna caves and the Istrian coast.
- Tito Square
- Venetian old town
- Postojna Cave
- Day3

Rijeka
Arrive 07:00 · Depart 15:00
Croatia's principal seaport, set where a river valley meets the Kvarner Gulf on the northern Adriatic. A working harbour city with a grand Habsburg-era core, it is crowned by the hilltop Trsat Castle and serves as a gateway to the nearby island of Krk.
- Trsat Castle
- Korzo promenade
- Kvarner Gulf
- Day4

Dubrovnik
Arrive 10:00 · Depart 20:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day5

Sarandë
Arrive 10:00 · Depart 20:00
A coastal town in southern Albania on the Ionian Sea, facing the Greek island of Corfu across a narrow strait. Its curved bay and beaches anchor the town, and the ancient ruins of Butrint lie a short way down the coast.
- Butrint ruins
- Ionian beaches
- Lëkurësi Castle
- Day6At sea
- Day7

Heraklion (Iraklion), Crete
Arrive 07:00 · Depart 17:00
The largest city on Crete and the island's main port, in Greece. A Venetian harbour and fortress front the town, while the Bronze Age palace of Knossos and the Heraklion Archaeological Museum's Minoan treasures lie close by.
- Palace of Knossos
- Venetian harbour
- Archaeological Museum
- Day8

Piraeus
Arrive 07:00 · Depart 19:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day9

Syros
Arrive 07:00 · Depart 17:00
- Day10

Bozcaada
Arrive 07:00 · Depart 15:00
- Day11

Istanbul
Arrive 08:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 5 May 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Mediterranean Cruise from Venice FAQ
Which ports does this cruise visit?
This 10-night Mediterranean cruise calls at Venice, Koper, Rijeka, Dubrovnik, Sarandë, Heraklion (Iraklion), Crete, Piraeus, Syros, Bozcaada and Istanbul.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Venice and ends in Istanbul.
How long is this cruise?
10 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 5 May 2027. A NestCruise advisor can confirm current availability.