Cruise itinerary
9-Night Europe Cruise from Istanbul
9 nights · Europe · 9 ports of call
9-night Europe cruise aboard Oceania Sirena, departing Istanbul and calling at Lesbos, Ephesus, Milos, Katakolon, Messina and Amalfi and 2 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Sirena
- Cruise line
- Oceania Cruises
- Duration
- 9 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Istanbul
- Returns
- Civitavecchia
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Sirena sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Istanbul
Arrive 07:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day2
Istanbul
Depart 16:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day3
Lesbos
Arrive 09:00 · Depart 17:00
- Day4
Ephesus
Arrive 07:00 · Depart 17:00
- Day5
Milos
Arrive 07:00 · Depart 16:00
A volcanic island in the Greek Cyclades, ringed by some of the most unusual coastline in the Aegean. The white cliffs and sea caves of Sarakiniko, the fishing village of Klima and the bay of Adamas draw visitors ashore.
- Sarakiniko cliffs
- Klima village
- Adamas harbour
- Day6
Katakolon
Arrive 07:00 · Depart 14:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day7
Messina
Arrive 09:00 · Depart 19:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day8
Amalfi
Arrive 07:00 · Depart 19:00
A cliff-clinging town on Italy's Amalfi Coast, once a powerful maritime republic. Its tiered houses rise from a small harbour to the striped facade of the Cathedral of St. Andrew, with lemon terraces and the scenic coast road threading along the shore.
- Amalfi Cathedral
- Lemon terraces
- Coast road drive
- Day9
Olbia
Arrive 11:00 · Depart 20:00
A port town on the northeast coast of Sardinia, set on a sheltered gulf and serving as the gateway to the Costa Smeralda. The surrounding coast is known for granite headlands and turquoise coves, while the old centre keeps Roman and medieval roots.
- Costa Smeralda
- San Simplicio basilica
- Granite coves
- Day10
Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
Upcoming departures
- 15 May 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
9-Night Europe Cruise from Istanbul FAQ
Which ports does this cruise visit?
This 9-night Europe cruise calls at Istanbul, Lesbos, Ephesus, Milos, Katakolon, Messina, Amalfi, Olbia and Civitavecchia.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Istanbul and ends in Civitavecchia.
How long is this cruise?
9 nights aboard Oceania Sirena.
When does this itinerary sail?
Upcoming departures include 15 May 2027. A NestCruise advisor can confirm current availability.