

Cruise itinerary
21-Night Mediterranean Cruise from Lisbon
21 nights · Mediterranean · 17 ports of call
21-night Mediterranean cruise aboard Silver Shadow, departing Lisbon and calling at Portimão, Cádiz, Seville, Valencia, Barcelona and Marseille and 10 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Silver Shadow
- Cruise line
- Silversea
- Duration
- 21 nights
- Region
- Mediterranean
- Departs
- Lisbon
- Returns
- Villefranche-sur-Mer
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Silver Shadow sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Lisbon
Depart 18:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day2

Portimão
Arrive 09:00 · Depart 19:00
A port town on the Algarve coast of southern Portugal, set at the mouth of the Arade River. It is known for grilled sardines and the golden cliffs and caves of nearby Praia da Rocha, one of the region's longest beaches.
- Praia da Rocha
- Grilled sardines
- Arade River
- Day3

Cádiz
Arrive 08:00 · Depart 23:00
One of the oldest continuously inhabited cities in Western Europe, set on a narrow spit almost surrounded by the Atlantic in Spain's Andalusia. A gold-domed cathedral rises over the old town's tight lanes, sea walls and the long sands of La Caleta.
- Cádiz Cathedral
- La Caleta beach
- Old town lanes
- Day4

Seville
Arrive 08:00 · Depart 18:00
Andalusia's historic capital, reached by river barge up the Guadalquivir in southern Spain. The vast Gothic cathedral, the Moorish Alcázar palace and the dancing of flamenco define a city once enriched by trade with the New World.
- Seville Cathedral
- Royal Alcázar
- Flamenco
- Day5At sea
- Day6At sea
- Day7

Valencia
Arrive 09:00 · Depart 17:00
Spain's third city, on the Mediterranean coast where the old riverbed has become a long ribbon of parkland. It is the birthplace of paella, home to the silk-era Lonja trading hall and to Calatrava's white City of Arts and Sciences complex.
- City of Arts and Sciences
- La Lonja
- Paella
- Day8

Barcelona
Arrive 08:00 · Depart 18:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day9

Marseille
Arrive 08:30 · Depart 17:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day10

Villefranche-sur-Mer
Arrive 07:00 · Depart 07:00
A deep-water bay on the French Riviera between Nice and Monaco, framed by steep pastel hillsides. The sheltered harbour is a classic tender anchorage, with a baroque old town behind the waterfront and easy connections along the coast to Nice and Monte Carlo.
- Old town
- Riviera coast
- Nice & Monaco access
- Day11

Portofino
Arrive 08:00 · Depart 19:00
A small fishing village on the Italian Riviera, its pastel houses curved around a sheltered harbour on a wooded promontory in Liguria. Long a retreat for yachts and writers, it has a tiny piazzetta, hillside church and coastal paths toward Genoa.
- Piazzetta harbour
- Castello Brown
- San Fruttuoso
- Day12

Livorno
Arrive 08:00 · Depart 18:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day13At sea
- Day14At sea
- Day15

Valletta
Arrive 08:00 · Depart 18:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day16

Giardini Naxos
Arrive 08:00 · Depart 18:00
A seaside resort on the east coast of Sicily, set along a sandy bay below the hilltop town of Taormina. Snow-capped Mount Etna rises inland, and the ancient Greek theatre and stepped streets of Taormina are a short ride up from the shore.
- Taormina
- Mount Etna
- Isola Bella
- Day17

Salerno
Arrive 09:00 · Depart 18:00
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day18

Sorrento
Arrive 08:00 · Depart 17:00
A clifftop town on Italy's Bay of Naples, perched above the sea facing Vesuvius. Sorrento is known for its lemon groves and limoncello, a tangle of narrow shopping lanes, and its role as a base for Capri, Pompeii, and the Amalfi Coast.
- Marina Grande
- Lemon groves
- Piazza Tasso
- Day19

Porto Santo Stefano
Arrive 09:00 · Depart 21:00
A fishing town and harbour on Tuscany's Monte Argentario promontory, looking across to the island of Giglio. Seafood restaurants line the waterfront, and the sandbars of the Orbetello lagoon and Maremma coast lie close by.
- Argentario coast
- Giglio ferry
- Orbetello lagoon
- Day20

Portoferraio
Arrive 08:00 · Depart 22:00
- Day21

Bastia
Arrive 08:00 · Depart 19:00
- Day22

Villefranche-sur-Mer
A deep-water bay on the French Riviera between Nice and Monaco, framed by steep pastel hillsides. The sheltered harbour is a classic tender anchorage, with a baroque old town behind the waterfront and easy connections along the coast to Nice and Monte Carlo.
- Old town
- Riviera coast
- Nice & Monaco access
Upcoming departures
- 23 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Mediterranean Cruise from Lisbon FAQ
Which ports does this cruise visit?
This 21-night Mediterranean cruise calls at Lisbon, Portimão, Cádiz, Seville, Valencia, Barcelona, Marseille, Villefranche-sur-Mer, Portofino, Livorno, Valletta, Giardini Naxos, Salerno, Sorrento, Porto Santo Stefano, Portoferraio and Bastia.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Lisbon and ends in Villefranche-sur-Mer.
How long is this cruise?
21 nights aboard Silver Shadow.
When does this itinerary sail?
Upcoming departures include 23 Mar 2027. A NestCruise advisor can confirm current availability.