

Cruise itinerary
14-Night South America Cruise from Cartagena
14 nights · South America · 6 ports of call
14-night South America cruise aboard Silver Shadow, departing Cartagena and calling at Panama Canal Transit, Panama City, Manta, Callao and Valparaiso.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Silver Shadow
- Cruise line
- Silversea
- Duration
- 14 nights
- Region
- South America
- Departs
- Cartagena
- Returns
- Valparaiso
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Silver Shadow sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Cartagena
Depart 23:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day2At sea
- Day3

Panama City
Arrive 19:00 · Depart 18:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day4At sea
- Day5At sea
- Day6At sea
- Day7

Manta
Arrive 08:00 · Depart 18:00
- Day8At sea
- Day9At sea
- Day10

Callao
Arrive 08:00 · Depart 22:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day11At sea
- Day12At sea
- Day13At sea
- Day14

Valparaiso
Arrive 13:30 · Depart 13:30
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day15

Valparaiso
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
Upcoming departures
- 15 Jan 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
14-Night South America Cruise from Cartagena FAQ
Which ports does this cruise visit?
This 14-night South America cruise calls at Cartagena, Panama Canal Transit, Panama City, Manta, Callao and Valparaiso.
How many days are spent at sea?
9 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Cartagena and ends in Valparaiso.
How long is this cruise?
14 nights aboard Silver Shadow.
When does this itinerary sail?
Upcoming departures include 15 Jan 2028. A NestCruise advisor can confirm current availability.