

Cruise itinerary
10-Night Mediterranean Cruise from Piraeus
10 nights · Mediterranean · 4 ports of call
10-night Mediterranean cruise aboard Seven Seas Voyager, departing Piraeus and calling at Heraklion (Iraklion), Crete, Rhodes and Istanbul.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 10 nights
- Region
- Mediterranean
- Departs
- Piraeus
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Voyager sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Piraeus
Arrive 22:00 · Depart 22:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day3At sea
- Day4

Heraklion (Iraklion), Crete
Arrive 08:00 · Depart 20:00
The largest city on Crete and the island's main port, in Greece. A Venetian harbour and fortress front the town, while the Bronze Age palace of Knossos and the Heraklion Archaeological Museum's Minoan treasures lie close by.
- Palace of Knossos
- Venetian harbour
- Archaeological Museum
- Day5At sea
- Day6At sea
- Day7

Rhodes
Arrive 08:00 · Depart 20:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day8At sea
- Day9At sea
- Day10

Istanbul
Arrive 08:00 · Depart 08:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11

Istanbul
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 24 Oct 2026
- 17 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Mediterranean Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 10-night Mediterranean cruise calls at Piraeus, Heraklion (Iraklion), Crete, Rhodes and Istanbul.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Istanbul.
How long is this cruise?
10 nights aboard Seven Seas Voyager.
When does this itinerary sail?
Upcoming departures include 24 Oct 2026 and 17 Nov 2026. A NestCruise advisor can confirm current availability.