

Cruise itinerary
23-Night Mediterranean Cruise from Lisbon
23 nights · Mediterranean · 16 ports of call
23-night Mediterranean cruise aboard Seven Seas Splendor, departing Lisbon and calling at Cádiz, Tangier, Málaga, Palma de Mallorca, Barcelona and Palamós and 9 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 23 nights
- Region
- Mediterranean
- Departs
- Lisbon
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Splendor sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Lisbon
Depart 17:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day2At sea
- Day3

Cádiz
Arrive 07:00 · Depart 22:00
One of the oldest continuously inhabited cities in Western Europe, set on a narrow spit almost surrounded by the Atlantic in Spain's Andalusia. A gold-domed cathedral rises over the old town's tight lanes, sea walls and the long sands of La Caleta.
- Cádiz Cathedral
- La Caleta beach
- Old town lanes
- Day4

Tangier
Arrive 08:00 · Depart 16:00
A Moroccan port at the mouth of the Strait of Gibraltar, where the Atlantic meets the Mediterranean and Europe lies in view across the water. Its walled medina and kasbah climb above the harbour, long a meeting point of African, Arab and European worlds.
- The Medina
- Kasbah
- Strait of Gibraltar
- Day5

Málaga
Arrive 07:00 · Depart 22:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day6At sea
- Day7

Palma de Mallorca
Arrive 08:00 · Depart 17:00
The capital of Mallorca in Spain's Balearic Islands, set around a wide bay. Its enormous seafront cathedral, La Seu, rises above the old town's narrow lanes, with a hilltop castle, marina and nearby coves a short way from the cruise terminal.
- La Seu cathedral
- Bellver Castle
- Old town
- Day8

Barcelona
Arrive 08:00 · Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day9

Palamós
Arrive 08:00 · Depart 17:00
A fishing town and marina on Spain's Costa Brava, north of Barcelona in Catalonia. Its working harbour and old quarter back onto a curve of beach, while the rocky coves and pine-clad coastline of the region stretch in both directions from the port.
- Costa Brava coves
- Town beach
- Fishing harbour
- Day10

Toulon
Arrive 08:30 · Depart 18:00
A major French naval port on the Mediterranean, set on a wide harbour beneath the heights of Mont Faron. Its old town and Provençal market lie behind the waterfront, and a cable car climbs the mountain for sweeping views over the roadstead.
- Mont Faron
- Provençal market
- Naval harbour
- Day11

Monte-Carlo
Arrive 08:00 · Depart 17:00
The seafront quarter of Monaco on the French Riviera, set on a rocky terrace above the Mediterranean. It is known for the belle-époque Casino, the Hôtel de Paris and the harbour that hosts the Monaco Grand Prix each spring.
- Casino de Monte-Carlo
- Port Hercule
- Grand Prix circuit
- Day12

Savona
Arrive 07:00 · Depart 19:00
- Day13

Livorno
Arrive 07:00 · Depart 19:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day14

Bastia
Arrive 08:00 · Depart 17:00
- Day15

Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day16At sea
- Day17

Dubrovnik
Arrive 09:00 · Depart 17:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day18At sea
- Day19At sea
- Day20

Piraeus
Arrive 05:30 · Depart 18:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day21At sea
- Day22At sea
- Day23

Istanbul
Arrive 07:00 · Depart 07:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day24

Istanbul
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 17 Oct 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
23-Night Mediterranean Cruise from Lisbon FAQ
Which ports does this cruise visit?
This 23-night Mediterranean cruise calls at Lisbon, Cádiz, Tangier, Málaga, Palma de Mallorca, Barcelona, Palamós, Toulon, Monte-Carlo, Savona, Livorno, Bastia, Civitavecchia, Dubrovnik, Piraeus and Istanbul.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Lisbon and ends in Istanbul.
How long is this cruise?
23 nights aboard Seven Seas Splendor.
When does this itinerary sail?
Upcoming departures include 17 Oct 2027. A NestCruise advisor can confirm current availability.