Cruise itinerary
12-Night Europe Cruise from Piraeus
12 nights · Europe · 11 ports of call
12-night Europe cruise aboard Seven Seas Splendor, departing Piraeus and calling at Cruising the Mediterranean Sea, Valletta, Naples, Civitavecchia, Livorno and Cannes and 4 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 12 nights
- Region
- Europe · Southern Europe · Mediterranean · Western Europe
- Departs
- Piraeus
- Returns
- Lisbon
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Splendor sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Piraeus
Arrive 05:30 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2
Cruising the Mediterranean Sea
- Day3
Valletta
Arrive 08:00 · Depart 15:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day4
Naples
Arrive 12:00 · Depart 20:30
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day5
Civitavecchia
Arrive 08:30 · Depart 20:30
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day6
Livorno
Arrive 08:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day7
Cannes
Arrive 07:00 · Depart 18:00
A glamorous resort town on the French Riviera, famous for its film festival and the palm-lined seafront promenade of La Croisette. The old quarter of Le Suquet climbs above the harbour, and Antibes and Grasse lie within easy reach along the coast.
- La Croisette
- Le Suquet
- Film festival
- Day8
Barcelona
Arrive 11:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day9
Barcelona
Depart 22:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day10
Cruising the Mediterranean Sea
- Day11
Málaga
Arrive 08:00 · Depart 20:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day12
Portimão
Arrive 10:30 · Depart 18:00
A port town on the Algarve coast of southern Portugal, set at the mouth of the Arade River. It is known for grilled sardines and the golden cliffs and caves of nearby Praia da Rocha, one of the region's longest beaches.
- Praia da Rocha
- Grilled sardines
- Arade River
- Day13
Lisbon
Arrive 07:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
Upcoming departures
- 11 Aug 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 12-night Europe cruise calls at Piraeus, Cruising the Mediterranean Sea, Valletta, Naples, Civitavecchia, Livorno, Cannes, Barcelona, Málaga, Portimão and Lisbon.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Lisbon.
How long is this cruise?
12 nights aboard Seven Seas Splendor.
When does this itinerary sail?
Upcoming departures include 11 Aug 2026. A NestCruise advisor can confirm current availability.