Cruise itinerary
11-Night Mediterranean Cruise from Istanbul
11 nights · Mediterranean · 11 ports of call
11-night Mediterranean cruise aboard Seven Seas Splendor, departing Istanbul and calling at Çanakkale, Kusadasi, Piraeus, Messina, Naples and Civitavecchia and 4 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 11 nights
- Region
- Mediterranean
- Departs
- Istanbul
- Returns
- Barcelona
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Splendor sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Istanbul
Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day2
Çanakkale
Arrive 07:00 · Depart 16:00
A Turkish port at the narrowest point of the Dardanelles strait, between the Aegean and the Sea of Marmara. It is the gateway to the ruins of ancient Troy and to the Gallipoli battlefields and war memorials across the water on the peninsula.
- Ancient Troy
- Gallipoli battlefields
- Dardanelles strait
- Day3
Kusadasi
Arrive 08:00 · Depart 17:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day4
Piraeus
Arrive 05:30 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day5At sea
- Day6
Messina
Arrive 08:00 · Depart 17:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day7
Naples
Arrive 08:00 · Depart 17:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day8
Civitavecchia
Arrive 07:00 · Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day9
Livorno
Arrive 07:00 · Depart 19:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day10
Toulon
Arrive 08:30 · Depart 18:00
A major French naval port on the Mediterranean, set on a wide harbour beneath the heights of Mont Faron. Its old town and Provençal market lie behind the waterfront, and a cable car climbs the mountain for sweeping views over the roadstead.
- Mont Faron
- Provençal market
- Naval harbour
- Day11
Palamós
Arrive 08:00 · Depart 17:00
A fishing town and marina on Spain's Costa Brava, north of Barcelona in Catalonia. Its working harbour and old quarter back onto a curve of beach, while the rocky coves and pine-clad coastline of the region stretch in both directions from the port.
- Costa Brava coves
- Town beach
- Fishing harbour
- Day12
Barcelona
Arrive 07:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
Upcoming departures
- 9 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
11-Night Mediterranean Cruise from Istanbul FAQ
Which ports does this cruise visit?
This 11-night Mediterranean cruise calls at Istanbul, Çanakkale, Kusadasi, Piraeus, Messina, Naples, Civitavecchia, Livorno, Toulon, Palamós and Barcelona.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Istanbul and ends in Barcelona.
How long is this cruise?
11 nights aboard Seven Seas Splendor.
When does this itinerary sail?
Upcoming departures include 9 Nov 2027. A NestCruise advisor can confirm current availability.