Cruise itinerary
14-Night Mediterranean Cruise from Civitavecchia
14 nights · Mediterranean · 14 ports of call
14-night Mediterranean cruise aboard Seven Seas Prestige, departing Civitavecchia and calling at Salerno, Messina, Kotor, Dubrovnik, Rijeka and Trieste and 7 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 14 nights
- Region
- Mediterranean
- Departs
- Civitavecchia
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Prestige sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Civitavecchia
Depart 16:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2
Salerno
Arrive 08:00 · Depart 17:00
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day3
Messina
Arrive 08:00 · Depart 17:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day4At sea
- Day5
Kotor
Arrive 08:00 · Depart 17:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day6
Dubrovnik
Arrive 07:00 · Depart 16:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day7
Rijeka
Arrive 11:00 · Depart 19:00
Croatia's principal seaport, set where a river valley meets the Kvarner Gulf on the northern Adriatic. A working harbour city with a grand Habsburg-era core, it is crowned by the hilltop Trsat Castle and serves as a gateway to the nearby island of Krk.
- Trsat Castle
- Korzo promenade
- Kvarner Gulf
- Day8
Trieste
Arrive 07:00 · Depart 16:00
A port city in northeast Italy near the Slovenian border, long the seaward gateway of the Austro-Hungarian Empire. Grand Habsburg-era squares open onto the Adriatic, with the seafront Piazza Unità d'Italia and the white Miramare Castle on the bay.
- Piazza Unità d'Italia
- Miramare Castle
- Viennese cafés
- Day9
Zadar
Arrive 07:00 · Depart 16:00
A walled Adriatic city on Croatia's Dalmatian coast, built on a compact peninsula of Roman and Venetian stone. Zadar is known for its waterfront Sea Organ, the solar Greeting to the Sun installation, and Roman ruins at the old forum.
- Sea Organ
- Roman Forum
- Greeting to the Sun
- Day10
Bari
Arrive 08:00 · Depart 16:00
A port city on Italy's Adriatic coast, the regional capital of Puglia at the country's southeastern heel. Its old quarter winds around the basilica of San Nicola, and home cooks hand-roll orecchiette pasta in the narrow lanes.
- Basilica di San Nicola
- Bari Vecchia
- Orecchiette
- Day11
Kefalonia (Argostoli), Greece
Arrive 10:00 · Depart 18:00
- Day12
Monemvasía
Arrive 10:00 · Depart 18:00
A fortified medieval town clinging to a tied island off the southeastern Peloponnese in Greece. A causeway links it to a lower town of Byzantine churches and stone lanes, with a ruined upper citadel crowning the rock above the Aegean.
- Lower town
- Byzantine churches
- Upper fortress
- Day13
Santorini
Arrive 08:00 · Depart 18:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day14
Mykonos
Arrive 08:00 · Depart 17:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day15
Piraeus
Arrive 05:30
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 22 Jul 2027
- 9 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
14-Night Mediterranean Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 14-night Mediterranean cruise calls at Civitavecchia, Salerno, Messina, Kotor, Dubrovnik, Rijeka, Trieste, Zadar, Bari, Kefalonia (Argostoli), Greece, Monemvasía, Santorini, Mykonos and Piraeus.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Piraeus.
How long is this cruise?
14 nights aboard Seven Seas Prestige.
When does this itinerary sail?
Upcoming departures include 22 Jul 2027 and 9 Sep 2027. A NestCruise advisor can confirm current availability.