Cruise itinerary
11-Night Americas Cruise from Miami, Florida
11 nights · Americas · 10 ports of call
11-night Americas cruise aboard Seven Seas Prestige, departing Miami, Florida and calling at Cruising the Florida Straits, Georgetown, Grand Cayman, Cruising the Caribbean Sea, Gatun Lake, Colón and Puerto Limón and 3 more.
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At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 11 nights
- Region
- Americas · South America · Panama Canal
- Departs
- Miami, Florida
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Prestige sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2
Cruising the Florida Straits
- Day3
Georgetown, Grand Cayman
Arrive 09:00 · Depart 18:00
Grand Cayman's capital and the main port of the Cayman Islands, set on the calm western shore. Cruise ships tender into the harbour beside Seven Mile Beach, with Stingray City sandbars and Caribbean reef diving a short boat ride away.
- Seven Mile Beach
- Stingray City
- Seven Mile reefs
- Day4
Cruising the Caribbean Sea
- Day5
Gatun Lake
Arrive 05:00 · Depart 15:00
Colón
Arrive 17:00 · Depart 20:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day6
Puerto Limón
Arrive 08:00 · Depart 17:00
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day7
Cruising the Caribbean Sea
- Day8
Roatán Island
Arrive 10:00 · Depart 18:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day9
Belize City
Arrive 07:00 · Depart 17:00
The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
- Barrier reef
- Maya ruins
- Cave tubing
- Day10
Cozumel
Arrive 08:00 · Depart 17:00
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day11
Cruising the Florida Straits
- Day12
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 9 Dec 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
11-Night Americas Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 11-night Americas cruise calls at Miami, Florida, Cruising the Florida Straits, Georgetown, Grand Cayman, Cruising the Caribbean Sea, Gatun Lake, Colón, Puerto Limón, Roatán Island, Belize City and Cozumel.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Miami, Florida.
How long is this cruise?
11 nights aboard Seven Seas Prestige.
When does this itinerary sail?
Upcoming departures include 9 Dec 2028. A NestCruise advisor can confirm current availability.