

Cruise itinerary
25-Night Americas Cruise from Miami, Florida
25 nights · Americas · 13 ports of call
25-night Americas cruise aboard Seven Seas Mariner, departing Miami, Florida and calling at Sailing the Atlantic Ocean, Bridgetown, Cruising the Amazon Central River, Brazil, Santarém, Boca de Valeria and Manaus and 6 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 25 nights
- Region
- Americas · South America
- Departs
- Miami, Florida
- Returns
- Buenos Aires
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Mariner sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Miami, Florida
Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2
Sailing the Atlantic Ocean
- Day3
Sailing the Atlantic Ocean
- Day4
Sailing the Atlantic Ocean
- Day5

Bridgetown
Arrive 07:00 · Depart 16:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day6
Sailing the Atlantic Ocean
- Day7
Sailing the Atlantic Ocean
- Day8

Cruising the Amazon Central River, Brazil
- Day9

Santarém
Arrive 09:00 · Depart 18:00
- Day10

Boca de Valeria
Arrive 07:00 · Depart 15:00
- Day11

Manaus
Arrive 09:30 · Depart 17:30
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day12

Parintins
Arrive 10:30 · Depart 18:30
- Day13

Alter do Chão
Arrive 07:00 · Depart 15:30
- Day14

Cruising the Amazon Central River, Brazil
- Day15
Sailing the Atlantic Ocean
- Day16
Sailing the Atlantic Ocean
- Day17
Sailing the Atlantic Ocean
- Day18
Sailing the Atlantic Ocean
- Day19
Sailing the Atlantic Ocean
- Day20

Rio de Janeiro
Arrive 11:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day21

Rio de Janeiro
Depart 16:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day22

Santos
Arrive 09:00 · Depart 18:00
Brazil's busiest port, on the coast of São Paulo state and the main gateway to that vast city. Its waterfront sits below green coastal hills, with historic coffee-trade buildings, an aquarium and long urban beaches backed by a seafront garden.
- Coffee Museum
- Santos beach gardens
- Pelé Museum
- Day23
Sailing the Atlantic Ocean
- Day24
Sailing the Atlantic Ocean
- Day25

Montevideo
Arrive 07:00 · Depart 17:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day26

Buenos Aires
Arrive 06:45 · Depart 18:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
Upcoming departures
- 7 Jan 2029
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
25-Night Americas Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 25-night Americas cruise calls at Miami, Florida, Sailing the Atlantic Ocean, Bridgetown, Cruising the Amazon Central River, Brazil, Santarém, Boca de Valeria, Manaus, Parintins, Alter do Chão, Rio de Janeiro, Santos, Montevideo and Buenos Aires.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Buenos Aires.
How long is this cruise?
25 nights aboard Seven Seas Mariner.
When does this itinerary sail?
Upcoming departures include 7 Jan 2029. A NestCruise advisor can confirm current availability.