

Cruise itinerary
20-Night Europe Cruise from Piraeus
20 nights · Europe · 16 ports of call
20-night Europe cruise aboard Seven Seas Mariner, departing Piraeus and calling at Khania, Santorini, Mykonos, Cruising the Aegean Sea, Bodrum and Kusadasi and 9 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 20 nights
- Region
- Europe · Southern Europe · Mediterranean · Greek Islands · Aegean
- Departs
- Piraeus
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Mariner sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Arrive 05:30 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Khania
Arrive 08:00 · Depart 17:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day3

Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day4

Mykonos
Arrive 08:00 · Depart 17:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day5
Cruising the Aegean Sea
- Day6

Bodrum
Arrive 08:00 · Depart 17:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day7

Kusadasi
Arrive 08:00 · Depart 17:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day8

Dikili
Arrive 08:00 · Depart 17:00
- Day9

Bozcaada
Arrive 08:00 · Depart 17:00
- Day10

Istanbul
Arrive 08:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11

Istanbul
Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day12
Cruising the Aegean Sea
- Day13

Rhodes
Arrive 07:00 · Depart 16:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day14

Limassol
Arrive 10:00 · Depart 18:00
A southern coastal city on Cyprus in the eastern Mediterranean, set around a long seafront promenade. A medieval castle anchors the old town, and the port is a base for the ancient ruins of Kourion and the wine villages of the Troodos foothills.
- Limassol Castle
- Kourion ruins
- seafront promenade
- Day15

Haifa
Arrive 06:00 · Depart 23:00
- Day16

Ashdod
Arrive 06:00 · Depart 23:00
- Day17
Cruising the Mediterranean Sea
- Day18

Alexandria
Arrive 06:00
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day19

Alexandria
Depart 22:00
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day20
Cruising the Mediterranean Sea
- Day21

Piraeus
Arrive 05:30 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 20 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
20-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 20-night Europe cruise calls at Piraeus, Khania, Santorini, Mykonos, Cruising the Aegean Sea, Bodrum, Kusadasi, Dikili, Bozcaada, Istanbul, Rhodes, Limassol, Haifa, Ashdod, Cruising the Mediterranean Sea and Alexandria.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Piraeus.
How long is this cruise?
20 nights aboard Seven Seas Mariner.
When does this itinerary sail?
Upcoming departures include 20 Sep 2027. A NestCruise advisor can confirm current availability.