Cruise itinerary
20-Night Mediterranean Cruise from Piraeus
20 nights · Mediterranean · 14 ports of call
20-night Mediterranean cruise aboard Seven Seas Mariner, departing Piraeus and calling at Soúda, Crete, Santorini, Mykonos, Bodrum, Kusadasi and Dikili and 7 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 20 nights
- Region
- Mediterranean
- Departs
- Piraeus
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Mariner sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2
Soúda, Crete
Arrive 08:00 · Depart 17:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day3
Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day4
Mykonos
Arrive 08:00 · Depart 17:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day5At sea
- Day6
Bodrum
Arrive 08:00 · Depart 17:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day7
Kusadasi
Arrive 08:00 · Depart 17:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day8
Dikili
Arrive 08:00 · Depart 17:00
- Day9
Bozcaada
Arrive 08:00 · Depart 17:00
- Day10
Istanbul
Arrive 08:00 · Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11At sea
- Day12At sea
- Day13
Rhodes
Arrive 07:00 · Depart 16:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day14
Limassol
Arrive 10:00 · Depart 18:00
A southern coastal city on Cyprus in the eastern Mediterranean, set around a long seafront promenade. A medieval castle anchors the old town, and the port is a base for the ancient ruins of Kourion and the wine villages of the Troodos foothills.
- Limassol Castle
- Kourion ruins
- seafront promenade
- Day15
Haifa
Arrive 06:00 · Depart 23:00
- Day16
Ashdod
Arrive 06:00 · Depart 23:00
- Day17At sea
- Day18
Alexandria
Arrive 06:00 · Depart 22:00
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day19At sea
- Day20At sea
- Day21
Piraeus
Arrive 05:30
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 20 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
20-Night Mediterranean Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 20-night Mediterranean cruise calls at Piraeus, Soúda, Crete, Santorini, Mykonos, Bodrum, Kusadasi, Dikili, Bozcaada, Istanbul, Rhodes, Limassol, Haifa, Ashdod and Alexandria.
How many days are spent at sea?
6 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Piraeus.
How long is this cruise?
20 nights aboard Seven Seas Mariner.
When does this itinerary sail?
Upcoming departures include 20 Sep 2027. A NestCruise advisor can confirm current availability.