

Cruise itinerary
10-Night Mediterranean Cruise from Piraeus
10 nights · Mediterranean · 9 ports of call
10-night Mediterranean cruise aboard Seven Seas Mariner, departing Piraeus and calling at Soúda, Crete, Santorini, Mykonos, Bodrum, Kusadasi and Dikili and 2 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 10 nights
- Region
- Mediterranean
- Departs
- Piraeus
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Mariner sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Soúda, Crete
Arrive 08:00 · Depart 17:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day3

Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day4

Mykonos
Arrive 08:00 · Depart 17:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day5At sea
- Day6

Bodrum
Arrive 08:00 · Depart 17:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day7

Kusadasi
Arrive 08:00 · Depart 17:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day8

Dikili
Arrive 08:00 · Depart 17:00
- Day9

Bozcaada
Arrive 08:00 · Depart 17:00
- Day10

Istanbul
Arrive 08:00 · Depart 08:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11

Istanbul
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 20 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Mediterranean Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 10-night Mediterranean cruise calls at Piraeus, Soúda, Crete, Santorini, Mykonos, Bodrum, Kusadasi, Dikili, Bozcaada and Istanbul.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Istanbul.
How long is this cruise?
10 nights aboard Seven Seas Mariner.
When does this itinerary sail?
Upcoming departures include 20 Sep 2027. A NestCruise advisor can confirm current availability.