

Cruise itinerary
5-Night Americas Cruise from Vancouver, British Columbia
5 nights · Americas · 4 ports of call
5-night Americas cruise aboard Serenade of the Seas, departing Vancouver, British Columbia and calling at Astoria, Oregon, San Francisco, California and San Diego, California.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Royal Caribbean International
- Duration
- 5 nights
- Region
- Americas · North America · West Coast US
- Departs
- Vancouver, British Columbia
- Returns
- San Diego, California
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Serenade of the Seas sailing, typically within 24 hours.
Where this voyage takes you
- Family Friendly
Day-by-day itinerary
- Day1

Vancouver, British Columbia
Depart 16:00
A Pacific coast city in British Columbia and the main homeport for Alaska cruises. Ships sail from beneath the sails of Canada Place, with Stanley Park's seawall, the totem poles and the cobbled Gastown district close to the terminal.
- Stanley Park
- Gastown
- Gateway to Alaska
- Day2

Astoria, Oregon
Arrive 10:30 · Depart 18:00
- Day3At sea
- Day4

San Francisco, California
Arrive 08:00 · Depart 20:00
A hill-built city on a peninsula between the Pacific and San Francisco Bay, known for the Golden Gate Bridge, cable cars, and Victorian rowhouses. Ships dock near the Embarcadero, within reach of Fisherman's Wharf, Chinatown, and ferries to Alcatraz.
- Golden Gate Bridge
- Cable cars
- Alcatraz Island
- Day5At sea
- Day6

San Diego, California
Arrive 07:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
Upcoming departures
- 27 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
5-Night Americas Cruise from Vancouver, British Columbia FAQ
Which ports does this cruise visit?
This 5-night Americas cruise calls at Vancouver, British Columbia, Astoria, Oregon, San Francisco, California and San Diego, California.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Vancouver, British Columbia and ends in San Diego, California.
How long is this cruise?
5 nights aboard Serenade of the Seas.
When does this itinerary sail?
Upcoming departures include 27 Sep 2026. A NestCruise advisor can confirm current availability.