Cruise itinerary
57-Night South America Cruise from Miami, Florida
57 nights · South America · 19 ports of call
57-night South America cruise aboard Seabourn Quest, departing Miami, Florida and calling at Panama Canal Transit, Panama City, Guayaquil, Salaverry, Callao and Pisco and 12 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Seabourn Quest
- Cruise line
- Seabourn
- Duration
- 57 nights
- Region
- South America
- Departs
- Miami, Florida
- Returns
- Buenos Aires
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seabourn Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2At sea
- Day3At sea
- Day4At sea
- Day5
Panama City
Arrive 21:00 · Depart 16:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day6At sea
- Day7At sea
- Day8At sea
- Day9
Guayaquil
Arrive 05:00 · Depart 18:00
- Day10At sea
- Day11
Salaverry
Arrive 05:00 · Depart 17:00
- Day12
Callao
Arrive 13:00 · Depart 21:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day13At sea
- Day14At sea
- Day15
Pisco
Arrive 08:00 · Depart 18:00
- Day16At sea
- Day17At sea
- Day18At sea
- Day19At sea
- Day20At sea
- Day21
Easter Island Chile
Arrive 08:00 · Depart 18:00
- Day22At sea
- Day23At sea
- Day24At sea
- Day25At sea
- Day26At sea
- Day27
Robinson Crusoe Island Chile
Arrive 09:00 · Depart 18:00
- Day28At sea
- Day29At sea
- Day30
Valparaiso
Arrive 07:00 · Depart 15:00
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day31At sea
- Day32
Puerto Montt
Arrive 10:00 · Depart 20:00
A port city in Chile's Lake District, set on the Reloncaví Sound where the central valley meets the fjords of Patagonia. Snow-capped volcanoes ring the bay, and the town is a launch point for trips to lakes, the German-influenced settlement of Puerto Varas and Chiloé island.
- Osorno Volcano
- Puerto Varas
- Angelmó market
- Day33
Chiloe Island Chile
Arrive 07:00 · Depart 16:00
- Day34
Puerto Chacabuco
Arrive 10:00 · Depart 19:00
- Day35At sea
- Day36
Chilean Fjords
Arrive 08:00 · Depart 18:00
- Day37At sea
- Day38
Punta Arenas
Arrive 10:00 · Depart 23:00
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day39At sea
- Day40At sea
- Day41
Ushuaia
Arrive 08:00 · Depart 19:00
The world's southernmost city, on Argentina's Tierra del Fuego at the tip of South America. Backed by snowy peaks on the Beagle Channel, it is the chief departure port for Antarctica and a base for the Patagonian wilderness.
- Beagle Channel
- Tierra del Fuego park
- End of the world
- Day42At sea
- Day43At sea
- Day44At sea
- Day45At sea
- Day46At sea
- Day47At sea
- Day48At sea
- Day49At sea
- Day50At sea
- Day51At sea
- Day52At sea
- Day53
Port Stanley
Arrive 07:00 · Depart 17:00
The small capital of the Falkland Islands in the South Atlantic, a row of brightly painted houses and tin roofs along a sheltered harbour. Penguin colonies and windswept moorland surround the settlement, with Christ Church Cathedral and its whalebone arch at the waterfront.
- Penguin colonies
- Whalebone Arch
- Christ Church Cathedral
- Day54At sea
- Day55At sea
- Day56At sea
- Day57
Montevideo
Arrive 07:00 · Depart 16:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day58
Buenos Aires
Arrive 07:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
Upcoming departures
- 7 Jan 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
57-Night South America Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 57-night South America cruise calls at Miami, Florida, Panama Canal Transit, Panama City, Guayaquil, Salaverry, Callao, Pisco, Easter Island Chile, Robinson Crusoe Island Chile, Valparaiso, Puerto Montt, Chiloe Island Chile, Puerto Chacabuco, Chilean Fjords, Punta Arenas, Ushuaia, Port Stanley, Montevideo and Buenos Aires.
How many days are spent at sea?
40 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Buenos Aires.
How long is this cruise?
57 nights aboard Seabourn Quest.
When does this itinerary sail?
Upcoming departures include 7 Jan 2028. A NestCruise advisor can confirm current availability.