

Cruise itinerary
14-Night Asia Cruise from Ho Chi Minh City
14 nights · Asia · 12 ports of call
14-night Asia cruise aboard Scenic Spirit, departing Ho Chi Minh City and calling at Mekong River Vietnam/Cambodia, Cái Bè, Sa Déc, Tân Châu, Border Crossing and Phnom Penh and 5 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scenic Spirit
- Cruise line
- Scenic
- Duration
- 14 nights
- Region
- Asia · Mekong
- Departs
- Ho Chi Minh City
- Returns
- Siem Reap
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scenic Spirit sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Ho Chi Minh City
Vietnam's largest city, still widely called Saigon, set on a river in the Mekong Delta region. French-era landmarks like the Notre-Dame basilica and Central Post Office sit amid motorbike-filled streets, with the Cu Chi tunnels reachable on a day trip.
- Notre-Dame Basilica
- Ben Thanh Market
- Cu Chi Tunnels
- Day2

Ho Chi Minh City
Vietnam's largest city, still widely called Saigon, set on a river in the Mekong Delta region. French-era landmarks like the Notre-Dame basilica and Central Post Office sit amid motorbike-filled streets, with the Cu Chi tunnels reachable on a day trip.
- Notre-Dame Basilica
- Ben Thanh Market
- Cu Chi Tunnels
- Day3

Ho Chi Minh City
Vietnam's largest city, still widely called Saigon, set on a river in the Mekong Delta region. French-era landmarks like the Notre-Dame basilica and Central Post Office sit amid motorbike-filled streets, with the Cu Chi tunnels reachable on a day trip.
- Notre-Dame Basilica
- Ben Thanh Market
- Cu Chi Tunnels
Mekong River Vietnam/Cambodia
- Day4

Cái Bè
- Day5

Sa Déc
- Day6

Tân Châu
A riverside town in An Giang Province on the Mekong Delta in southern Vietnam, near the Cambodian border. Tân Châu is known for its silk-weaving tradition, floating fish farms, and as a quiet stop on Mekong river cruises.
- Silk weaving
- Mekong fish farms
- Delta villages
- Day7
Border Crossing

Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront
- Day8

Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront
- Day9

Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront

Oudong
Koh Dach Island, Phnom Penh
- Day10

Angkor Ban
- Day11

Kampong Cham
A riverside provincial town on the Mekong in eastern Cambodia, long a trading and rubber-growing hub. Nearby stand the hilltop temples of Phnom Pros and Phnom Srei and the early Angkorian shrine of Wat Nokor.
- Wat Nokor
- Bamboo bridge
- Mekong riverfront

Kampong Cham
A riverside provincial town on the Mekong in eastern Cambodia, long a trading and rubber-growing hub. Nearby stand the hilltop temples of Phnom Pros and Phnom Srei and the early Angkorian shrine of Wat Nokor.
- Wat Nokor
- Bamboo bridge
- Mekong riverfront
- Day12

Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
- Day13

Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
- Day14

Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
- Day15

Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
Upcoming departures
- 19 Jul 2026
- 27 Jul 2026
- 6 Aug 2026
- 14 Aug 2026
- 24 Aug 2026
- 1 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
14-Night Asia Cruise from Ho Chi Minh City FAQ
Which ports does this cruise visit?
This 14-night Asia cruise calls at Ho Chi Minh City, Mekong River Vietnam/Cambodia, Cái Bè, Sa Déc, Tân Châu, Border Crossing, Phnom Penh, Oudong, Koh Dach Island, Phnom Penh, Angkor Ban, Kampong Cham and Siem Reap.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Ho Chi Minh City and ends in Siem Reap.
How long is this cruise?
14 nights aboard Scenic Spirit.
When does this itinerary sail?
Upcoming departures include 19 Jul 2026, 27 Jul 2026, 6 Aug 2026 and 14 Aug 2026. A NestCruise advisor can confirm current availability.