

Cruise itinerary
12-Night Mekong Cruise from Saigon
12 nights · Mekong · 10 ports of call
12-night Mekong cruise aboard Scenic Spirit, departing Saigon and calling at Cái Bè, Sa Déc, Tân Châu, Phnom Penh, Oudong and Angkor Ban and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scenic Spirit
- Cruise line
- Scenic
- Duration
- 12 nights
- Region
- Mekong · Southeast Asia
- Departs
- Saigon
- Returns
- Luang Prabang
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scenic Spirit sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Saigon
- Day2At sea
- Day3At sea
- Day4

Sa Déc
- Day5

Tân Châu
A riverside town in An Giang Province on the Mekong Delta in southern Vietnam, near the Cambodian border. Tân Châu is known for its silk-weaving tradition, floating fish farms, and as a quiet stop on Mekong river cruises.
- Silk weaving
- Mekong fish farms
- Delta villages
- Day6

Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront
- Day7

Oudong
- Day8

Angkor Ban
- Day9

Kampong Cham
A riverside provincial town on the Mekong in eastern Cambodia, long a trading and rubber-growing hub. Nearby stand the hilltop temples of Phnom Pros and Phnom Srei and the early Angkorian shrine of Wat Nokor.
- Wat Nokor
- Bamboo bridge
- Mekong riverfront
- Day10

Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
- Day11At sea
- Day12At sea
- Day13

Luang Prabang
Upcoming departures
- 26 Sep 2027
- 10 Oct 2027
- 24 Oct 2027
- 21 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Mekong Cruise from Saigon FAQ
Which ports does this cruise visit?
This 12-night Mekong cruise calls at Saigon, Cái Bè, Sa Déc, Tân Châu, Phnom Penh, Oudong, Angkor Ban, Kampong Cham, Siem Reap and Luang Prabang.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Saigon and ends in Luang Prabang.
How long is this cruise?
12 nights aboard Scenic Spirit.
When does this itinerary sail?
Upcoming departures include 26 Sep 2027, 10 Oct 2027, 24 Oct 2027 and 21 Nov 2027. A NestCruise advisor can confirm current availability.