

Cruise itinerary
17-Night Rhine Cruise from Brussels
17 nights · Rhine · 16 ports of call
17-night Rhine cruise aboard Scenic Ruby, departing Brussels and calling at Zeebrugge, Amsterdam, Dordrecht, Bruinisse, Antwerp and Arnhem and 9 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scenic Ruby
- Cruise line
- Scenic
- Duration
- 17 nights
- Region
- Rhine · Europe
- Departs
- Brussels
- Returns
- Basel
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scenic Ruby sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Zeebrugge
A North Sea port on the Belgian coast and the gateway to Bruges, about a quarter-hour inland by road. Zeebrugge itself is a working harbour and beach resort, while nearby Bruges draws visitors for its canals, belfry, and medieval market square.
- Bruges canals
- Belfry of Bruges
- Coastal tram
- Day2At sea
- Day3At sea
- Day4

Amsterdam
The Dutch capital, laced with concentric canals and gabled merchant houses from its 17th-century golden age. Most river sailings depart from here, leaving time for the Rijksmuseum, the Anne Frank House or a stroll through the Jordaan before lines cast off.
- Rijksmuseum
- Anne Frank House
- Jordaan canals
- Day5

Dordrecht
One of the oldest cities in the Netherlands, set where three rivers meet in the province of South Holland. Its historic centre holds canalside merchant houses, the Grote Kerk and a working harbour, with the windmills of Kinderdijk nearby.
- Grote Kerk
- Historic harbour
- Kinderdijk windmills
- Day6

Bruinisse
- Day7

Antwerp
A Belgian port city on the Scheldt and one of Europe's largest harbours. Its medieval Grote Markt and Gothic Cathedral of Our Lady anchor the old centre, in a city long tied to Rubens, diamond trading and Flemish art.
- Grote Markt
- Cathedral of Our Lady
- Diamond district
- Day8

Arnhem
- Day9

Düsseldorf
A city on the Rhine in western Germany, capital of North Rhine-Westphalia and a hub of fashion and finance. Düsseldorf is known for the historic Altstadt and its rows of taverns, the riverside promenade, and the modern architecture of the MedienHafen.
- Altstadt taverns
- Rhine promenade
- MedienHafen
- Day10At sea
- Day11

Cochem
A small wine town on a horseshoe bend of the Moselle in western Germany. Half-timbered houses surround its market square, terraced Riesling vineyards rise on the slopes, and the Reichsburg castle looks down from the hill above.
- Reichsburg castle
- Riesling vineyards
- Market square
- Day12

Bernkastel-Kues
A picturesque wine town on the Moselle in Germany, famous among Riesling growers. Half-timbered houses crowd the sloping market square, the ruined Landshut castle stands above, and steep vineyards line the river on either bank.
- Marktplatz houses
- Landshut castle
- Moselle Riesling
- Day13

Koblenz
A German city at the meeting of the Rhine and Moselle rivers, the point known as the Deutsches Eck or 'German Corner'. A cable car climbs from the headland to the Ehrenbreitstein fortress, and the town marks the northern end of the Rhine Gorge.
- Deutsches Eck
- Ehrenbreitstein Fortress
- Rhine cable car
- Day14

Rüdesheim am Rhein
A wine town on the Rhine in Germany's Rheingau, set among steep Riesling vineyards. Its narrow Drosselgasse lane is lined with taverns, and a cable car rises to the Niederwald monument overlooking the river gorge.
- Drosselgasse lane
- Niederwald monument
- Rheingau vineyards
- Day15

Mannheim
A city in southwest Germany where the Neckar meets the Rhine, laid out on a grid of numbered blocks rather than street names. The baroque palace is among Europe's largest, and the water tower anchors a green boulevard through the centre.
- Mannheim Palace
- Wasserturm
- Squares grid
- Day16

Kehl
A German town on the right bank of the Rhine, directly across the river from Strasbourg in France. A bridge and garden link the two banks, and the riverside park makes it a crossing point for cruises between Germany and Alsace.
- Two Banks Garden
- Rhine bridge
- Strasbourg nearby
- Day17

Breisach
A small town on the Rhine at the edge of Germany's Kaiserstuhl wine country, just across the river from France's Alsace. It is crowned by the St. Stephan minster on its hilltop and serves as the river gateway to Freiburg and the southern Black Forest.
- St. Stephan minster
- Kaiserstuhl vineyards
- Black Forest gateway
- Day18

Basel
A Swiss city on the Rhine where Switzerland, France and Germany meet, and a common starting point for Rhine cruises. Its old town climbs from the river to a red sandstone cathedral and a medieval market square ringed by guild houses.
- Basel Münster
- Old town
- Rhine starting point
Upcoming departures
- 17 May 2026
- 13 Sep 2026
- 19 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
17-Night Rhine Cruise from Brussels FAQ
Which ports does this cruise visit?
This 17-night Rhine cruise calls at Brussels, Zeebrugge, Amsterdam, Dordrecht, Bruinisse, Antwerp, Arnhem, Düsseldorf, Cochem, Bernkastel-Kues, Koblenz, Rüdesheim am Rhein, Mannheim, Kehl, Breisach and Basel.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Brussels and ends in Basel.
How long is this cruise?
17 nights aboard Scenic Ruby.
When does this itinerary sail?
Upcoming departures include 17 May 2026, 13 Sep 2026 and 19 Sep 2027. A NestCruise advisor can confirm current availability.