Cruise itinerary
22-Night Rhone Cruise from Amsterdam
22 nights · Rhone · 21 ports of call
22-night Rhone cruise aboard Scenic Pearl, departing Amsterdam and calling at Dordrecht, Bruinisse, Antwerp, Arnhem, Düsseldorf and Cochem and 14 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scenic Pearl
- Cruise line
- Scenic
- Duration
- 22 nights
- Region
- Rhone · Rhine · Europe
- Departs
- Amsterdam
- Returns
- Lyon
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scenic Pearl sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Amsterdam
The Dutch capital, laced with concentric canals and gabled merchant houses from its 17th-century golden age. Most river sailings depart from here, leaving time for the Rijksmuseum, the Anne Frank House or a stroll through the Jordaan before lines cast off.
- Rijksmuseum
- Anne Frank House
- Jordaan canals
- Day2
Dordrecht
One of the oldest cities in the Netherlands, set where three rivers meet in the province of South Holland. Its historic centre holds canalside merchant houses, the Grote Kerk and a working harbour, with the windmills of Kinderdijk nearby.
- Grote Kerk
- Historic harbour
- Kinderdijk windmills
- Day3
Bruinisse
- Day4
Antwerp
A Belgian port city on the Scheldt and one of Europe's largest harbours. Its medieval Grote Markt and Gothic Cathedral of Our Lady anchor the old centre, in a city long tied to Rubens, diamond trading and Flemish art.
- Grote Markt
- Cathedral of Our Lady
- Diamond district
- Day5
Arnhem
- Day6
Düsseldorf
A city on the Rhine in western Germany, capital of North Rhine-Westphalia and a hub of fashion and finance. Düsseldorf is known for the historic Altstadt and its rows of taverns, the riverside promenade, and the modern architecture of the MedienHafen.
- Altstadt taverns
- Rhine promenade
- MedienHafen
- Day7At sea
- Day8
Cochem
A small wine town on a horseshoe bend of the Moselle in western Germany. Half-timbered houses surround its market square, terraced Riesling vineyards rise on the slopes, and the Reichsburg castle looks down from the hill above.
- Reichsburg castle
- Riesling vineyards
- Market square
- Day9
Bernkastel-Kues
A picturesque wine town on the Moselle in Germany, famous among Riesling growers. Half-timbered houses crowd the sloping market square, the ruined Landshut castle stands above, and steep vineyards line the river on either bank.
- Marktplatz houses
- Landshut castle
- Moselle Riesling
- Day10
Koblenz
A German city at the meeting of the Rhine and Moselle rivers, the point known as the Deutsches Eck or 'German Corner'. A cable car climbs from the headland to the Ehrenbreitstein fortress, and the town marks the northern end of the Rhine Gorge.
- Deutsches Eck
- Ehrenbreitstein Fortress
- Rhine cable car
- Day11
Rüdesheim am Rhein
A wine town on the Rhine in Germany's Rheingau, set among steep Riesling vineyards. Its narrow Drosselgasse lane is lined with taverns, and a cable car rises to the Niederwald monument overlooking the river gorge.
- Drosselgasse lane
- Niederwald monument
- Rheingau vineyards
- Day12
Mannheim
A city in southwest Germany where the Neckar meets the Rhine, laid out on a grid of numbered blocks rather than street names. The baroque palace is among Europe's largest, and the water tower anchors a green boulevard through the centre.
- Mannheim Palace
- Wasserturm
- Squares grid
- Day13
Kehl
A German town on the right bank of the Rhine, directly across the river from Strasbourg in France. A bridge and garden link the two banks, and the riverside park makes it a crossing point for cruises between Germany and Alsace.
- Two Banks Garden
- Rhine bridge
- Strasbourg nearby
- Day14
Breisach
A small town on the Rhine at the edge of Germany's Kaiserstuhl wine country, just across the river from France's Alsace. It is crowned by the St. Stephan minster on its hilltop and serves as the river gateway to Freiburg and the southern Black Forest.
- St. Stephan minster
- Kaiserstuhl vineyards
- Black Forest gateway
- Day15
Lyon
A French city at the meeting of the Rhône and Saône rivers, long regarded as the country's gastronomic capital. Its Renaissance old town hides covered passages called traboules, while the Fourvière basilica crowns the hill above the two rivers.
- Vieux Lyon traboules
- Fourvière Basilica
- Bouchon dining
- Day16
Mâcon
A river town in eastern France on the Saône, at the southern edge of Burgundy. It serves the celebrated Mâconnais and Beaujolais vineyards, with the rock of Solutré rising over the slopes and a Romanesque heritage in the surrounding villages.
- Mâconnais wine
- Rock of Solutré
- Saône riverfront
- Day17
Vienne
- Day18
Tournon-sur-Rhône
A small town on the Rhône in southern France, facing the steep Hermitage vineyards across the river at Tain. A medieval castle overlooks the water, and the surrounding northern Rhône slopes are known for their Syrah wines.
- Hermitage vineyards
- Hilltop château
- Rhône wines
- Day19
Avignon
A walled city on the Rhône in Provence, southern France, once the seat of medieval popes. The vast Palais des Papes dominates the centre, and the broken Pont d'Avignon reaches partway across the river below the ramparts.
- Palais des Papes
- Pont d'Avignon
- City ramparts
- Day20At sea
- Day21
Arles
A Provençal town on the Rhône River in southern France, ringed by Roman monuments. Its great amphitheatre still hosts events, and the surrounding light and streets inspired the painter Van Gogh during his year in the town.
- Roman amphitheatre
- Van Gogh sites
- Place du Forum
- Day22
Viviers-sur-Rhone
- Day23
Lyon
A French city at the meeting of the Rhône and Saône rivers, long regarded as the country's gastronomic capital. Its Renaissance old town hides covered passages called traboules, while the Fourvière basilica crowns the hill above the two rivers.
- Vieux Lyon traboules
- Fourvière Basilica
- Bouchon dining
Upcoming departures
- 29 Jul 2026
- 1 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
22-Night Rhone Cruise from Amsterdam FAQ
Which ports does this cruise visit?
This 22-night Rhone cruise calls at Amsterdam, Dordrecht, Bruinisse, Antwerp, Arnhem, Düsseldorf, Cochem, Bernkastel-Kues, Koblenz, Rüdesheim am Rhein, Mannheim, Kehl, Breisach, Basel, Lyon, Mâcon, Vienne, Tournon-sur-Rhône, Avignon, Arles and Viviers-sur-Rhone.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Amsterdam and ends in Lyon.
How long is this cruise?
22 nights aboard Scenic Pearl.
When does this itinerary sail?
Upcoming departures include 29 Jul 2026 and 1 Sep 2027. A NestCruise advisor can confirm current availability.