Cruise itinerary
21-Night Seine Cruise from Lisbon
21 nights · Seine · 15 ports of call
21-night Seine cruise aboard Scenic Azure, departing Lisbon and calling at Porto-Vecchio, Entre-os-Rios, Régua, Vega de Terrón, Pocinho and Pinhão and 8 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scenic Azure
- Cruise line
- Scenic
- Duration
- 21 nights
- Region
- Seine · Europe
- Departs
- Lisbon
- Returns
- Paris
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scenic Azure sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Lisbon
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day2At sea
- Day3At sea
- Day4
Porto-Vecchio
- Day5
Entre-os-Rios
- Day6
Régua
A small town on the Douro River in northern Portugal, deep in the terraced vineyards of the port-wine country. River vessels moor here to reach hilltop quintas and wine estates, with the steep, schist-walled valley rising on both banks.
- Douro vineyards
- Port-wine quintas
- Terraced hillsides
- Day7At sea
- Day8
Vega de Terrón
A tiny river quay on the Duero in western Spain, near the Portuguese border, serving as the turnaround point for Douro Valley cruises. It sits amid the terraced vineyards and granite uplands of the Arribes region, with the walled town of Salamanca reached by road.
- Douro vineyards
- Salamanca day trip
- Arribes gorge
- Day9
Pocinho
A small terminal in Portugal's Upper Douro, deep in the terraced wine country of the river valley. It serves the vineyards that produce port wine, the rock-art site at Foz Côa and the quiet villages stepping down to the water.
- Douro vineyards
- Côa rock art
- Terraced slopes
- Day10
Pinhão
A small riverside town in the heart of Portugal's Douro Valley, the world's oldest demarcated wine region. Terraced vineyards rise steeply from the water on every side, and the historic railway station is lined with hand-painted azulejo tile panels.
- Douro vineyards
- Azulejo station
- Port wine quintas
- Day11At sea
- Day12
Porto-Vecchio
- Day13At sea
- Day14
Paris
The French capital on the Seine, the start or finish of many river cruises through northern France. Ships moor near the centre, putting the Eiffel Tower, the Louvre and Notre-Dame within easy reach across a city built for walking.
- Eiffel Tower
- The Louvre
- Notre-Dame
- Day15
Les Andelys
A small town on a loop of the Seine in Normandy, France, overlooked by the ruined Château Gaillard. Richard the Lionheart's clifftop fortress dominates the river bend, and the surrounding valley of chalk cliffs and orchards is classic Norman countryside.
- Château Gaillard
- Seine valley
- Norman countryside
- Day16
Rouen
A historic city on the Seine in Normandy, where river ships moor within walking distance of the centre. Its medieval old town keeps half-timbered houses and a soaring Gothic cathedral, and it is the place where Joan of Arc was put to death in 1431.
- Rouen Cathedral
- Old town
- Joan of Arc
- Day17At sea
- Day18
Honfleur
A picturesque harbour town at the mouth of the Seine in Normandy, France, its tall slate-fronted houses ringing the old basin. The port inspired the Impressionist painters, and it lies within reach of the Normandy landing beaches and the city of Rouen.
- Vieux Bassin
- Sainte-Catherine church
- Normandy beaches
- Day19At sea
- Day20
Rives-en-Seine
- Day21
Chateau de La Roche-Guyon
- Day22
Paris
The French capital on the Seine, the start or finish of many river cruises through northern France. Ships moor near the centre, putting the Eiffel Tower, the Louvre and Notre-Dame within easy reach across a city built for walking.
- Eiffel Tower
- The Louvre
- Notre-Dame
Upcoming departures
- 10 Apr 2027
- 7 May 2027
- 17 May 2027
- 6 Aug 2027
- 16 Aug 2027
- 2 Sep 2027
- 12 Sep 2027
- 29 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Seine Cruise from Lisbon FAQ
Which ports does this cruise visit?
This 21-night Seine cruise calls at Lisbon, Porto-Vecchio, Entre-os-Rios, Régua, Vega de Terrón, Pocinho, Pinhão, Paris, Les Andelys, Rouen, Honfleur, Rives-en-Seine, Vernon, Chateau de La Roche-Guyon and Conflans-Sainte-Honorine.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Lisbon and ends in Paris.
How long is this cruise?
21 nights aboard Scenic Azure.
When does this itinerary sail?
Upcoming departures include 10 Apr 2027, 7 May 2027, 17 May 2027 and 6 Aug 2027. A NestCruise advisor can confirm current availability.