Cruise itinerary
12-Night Europe Cruise from Rome
12 nights · Europe · 11 ports of call
12-night Europe cruise aboard Scarlet Lady, departing Rome and calling at Florence, At Sea, Capri, Palermo, Valletta and Khania and 4 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scarlet Lady
- Cruise line
- Virgin Voyages
- Duration
- 12 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Rome
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scarlet Lady sailing, typically within 24 hours.
Where this voyage takes you
- Adults Only
Day-by-day itinerary
- Day1
Rome
Depart 20:00
- Day2
Florence
Arrive 08:00 · Depart 20:00
- Day3
At Sea
- Day4
Capri
Arrive 08:00 · Depart 19:00
- Day5
Palermo
Arrive 08:00 · Depart 17:00
The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
- Cappella Palatina
- Ballarò market
- Monreale mosaics
- Day6
Valletta
Arrive 09:30 · Depart 17:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day7
At Sea
- Day8
Khania
Arrive 08:00 · Depart 18:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day9
Mykonos
Arrive 08:00 · Depart 20:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day10
Santorini
Arrive 08:00 · Depart 18:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day11
Kusadasi
Arrive 08:00 · Depart 18:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day12
At Sea
- Day13
Piraeus
Arrive 06:30
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 7 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Europe Cruise from Rome FAQ
Which ports does this cruise visit?
This 12-night Europe cruise calls at Rome, Florence, At Sea, Capri, Palermo, Valletta, Khania, Mykonos, Santorini, Kusadasi and Piraeus.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Rome and ends in Piraeus.
How long is this cruise?
12 nights aboard Scarlet Lady.
When does this itinerary sail?
Upcoming departures include 7 Sep 2027. A NestCruise advisor can confirm current availability.