

Cruise itinerary
7-Night Galapagos Islands Cruise from Quito
7 nights · Galapagos Islands · 12 ports of call
7-night Galapagos Islands cruise aboard MS Santa Cruz II, departing Quito and calling at flight, Baltra Island, Mosquera Island, San Cristobal Island, Santa Fe Island and South Plaza Island and 5 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MS Santa Cruz II
- Cruise line
- HX Expeditions
- Duration
- 7 nights
- Region
- Galapagos Islands
- Departs
- Quito
- Returns
- Guayaquil
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MS Santa Cruz II sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Quito
- Day2
Mosquera Island
- Day3

San Cristobal Island
- Day4
South Plaza Island
- Day5

Santa Cruz Island
- Day6

Espanola Island
- Day7
North Seymour Island
- Day8

Guayaquil
Upcoming departures
- 4 Jun 2026
- 18 Jun 2026
- 2 Jul 2026
- 16 Jul 2026
- 30 Jul 2026
- 27 Aug 2026
- 10 Sep 2026
- 24 Sep 2026
- 8 Oct 2026
- 22 Oct 2026
- 5 Nov 2026
- 19 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
7-Night Galapagos Islands Cruise from Quito FAQ
Which ports does this cruise visit?
This 7-night Galapagos Islands cruise calls at Quito, flight, Baltra Island, Mosquera Island, San Cristobal Island, Santa Fe Island, South Plaza Island, Santa Cruz Island, Espanola Island, Eden Island, North Seymour Island and Guayaquil.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Quito and ends in Guayaquil.
How long is this cruise?
7 nights aboard MS Santa Cruz II.
When does this itinerary sail?
Upcoming departures include 4 Jun 2026, 18 Jun 2026, 2 Jul 2026 and 16 Jul 2026. A NestCruise advisor can confirm current availability.