Cruise itinerary
19-Night Mediterranean Cruise from Southampton
19 nights · Mediterranean · 9 ports of call
19-night Mediterranean cruise aboard Queen Anne, departing Southampton and calling at Cadiz, Mykonos Island, Santorini Island, Piraeus-Athens, Heraklion and Katakolon and 2 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Queen Anne
- Cruise line
- Cunard
- Duration
- 19 nights
- Region
- Mediterranean
- Departs
- Southampton
- Returns
- Southampton
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Queen Anne sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Southampton
England's principal cruise homeport on the south coast, with deep docks that once launched the great ocean liners. Many transatlantic and Northern European sailings begin here, an hour or so by rail from London and close to the New Forest.
- Ocean liner heritage
- Gateway to London
- Tudor old town
- Day2At sea
- Day3At sea
- Day4
Cadiz
One of the oldest continuously inhabited cities in Western Europe, set on a narrow spit almost surrounded by the Atlantic in Spain's Andalusia. A gold-domed cathedral rises over the old town's tight lanes, sea walls and the long sands of La Caleta.
- Cádiz Cathedral
- La Caleta beach
- Old town lanes
- Day5At sea
- Day6At sea
- Day7At sea
- Day8
Mykonos Island
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day9
Santorini Island
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day10
Piraeus-Athens
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day11
Heraklion
- Day12At sea
- Day13
Katakolon
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day14At sea
- Day15
Cagliari
The capital of Sardinia, an Italian port set across hills above the Gulf of the Angels. Its fortified Castello quarter looks down over the harbour, with a long city beach at Poetto and the Roman amphitheatre among its older landmarks.
- Castello quarter
- Poetto Beach
- Roman amphitheatre
- Day16At sea
- Day17
Gibraltar
A British territory at the southern tip of Spain, dominated by its towering limestone Rock. Cable cars climb to the summit, home to Europe's only wild monkeys, with sweeping views across the strait toward the coast of Africa.
- The Rock
- Barbary macaques
- St. Michael's Cave
- Day18At sea
- Day19At sea
- Day20
Southampton
England's principal cruise homeport on the south coast, with deep docks that once launched the great ocean liners. Many transatlantic and Northern European sailings begin here, an hour or so by rail from London and close to the New Forest.
- Ocean liner heritage
- Gateway to London
- Tudor old town
Upcoming departures
- 20 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
19-Night Mediterranean Cruise from Southampton FAQ
Which ports does this cruise visit?
This 19-night Mediterranean cruise calls at Southampton, Cadiz, Mykonos Island, Santorini Island, Piraeus-Athens, Heraklion, Katakolon, Cagliari and Gibraltar.
How many days are spent at sea?
10 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Southampton.
How long is this cruise?
19 nights aboard Queen Anne.
When does this itinerary sail?
Upcoming departures include 20 Sep 2026. A NestCruise advisor can confirm current availability.