

Cruise itinerary
38-Night Mediterranean Cruise from Piraeus
38 nights · Mediterranean · 28 ports of call
38-night Mediterranean cruise aboard Azamara Onward, departing Piraeus and calling at Syros, Pátmos, Marmaris, Rhodes, Agios Nikólaos, Kríti and Santorini and 21 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Azamara Onward
- Cruise line
- Azamara
- Duration
- 38 nights
- Region
- Mediterranean
- Departs
- Piraeus
- Returns
- Lisbon
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Azamara Onward sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Depart 18:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Syros
Arrive 08:00 · Depart 20:00
- Day3

Pátmos
Arrive 08:00 · Depart 20:00
A small Greek island in the Dodecanese, long held sacred in Christian tradition. The hilltop Monastery of Saint John crowns the whitewashed Chóra, near the cave where the Book of Revelation is said to have been written above the harbour at Skala.
- Monastery of St. John
- Cave of the Apocalypse
- Chóra hilltop
- Day4

Marmaris
Arrive 08:00 · Depart 22:00
- Day5

Rhodes
Arrive 08:00 · Depart 22:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day6

Agios Nikólaos, Kríti
Arrive 08:00 · Depart 20:00
A resort town on the eastern coast of Crete, built around the small saltwater Lake Voulismeni at the edge of the harbour. It looks out over the Gulf of Mirabello toward Spinalonga, the former Venetian fortress and leper colony on its islet.
- Lake Voulismeni
- Spinalonga island
- Mirabello Gulf
- Day7

Santorini
Arrive 08:00 · Depart 18:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day8

Piraeus
Arrive 05:00 · Depart 05:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day9

Mykonos
Arrive 08:00 · Depart 20:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day10

Bodrum
Arrive 08:00 · Depart 22:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day11

Heraklion (Iraklion), Crete
Arrive 09:00 · Depart 20:00
The largest city on Crete and the island's main port, in Greece. A Venetian harbour and fortress front the town, while the Bronze Age palace of Knossos and the Heraklion Archaeological Museum's Minoan treasures lie close by.
- Palace of Knossos
- Venetian harbour
- Archaeological Museum
- Day12At sea
- Day13

Alexandria
Arrive 06:00 · Depart 20:00
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day14At sea
- Day15At sea
- Day16At sea
- Day17

Valletta
Arrive 08:00 · Depart 22:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day18
Siracusa, Sicily
Arrive 08:00 · Depart 22:00
- Day19

Catania
Arrive 08:00 · Depart 16:00
A port city on the east coast of Sicily, built in dark volcanic stone beneath Mount Etna, Europe's most active volcano. Its baroque centre, rebuilt after earthquakes, is known for the elephant fountain, a fish market, and Etna excursions inland.
- Mount Etna
- Baroque centre
- Fish market
- Day20

Salerno
Arrive 08:00 · Depart 16:00
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day21At sea
- Day22

Civitavecchia
Arrive 06:00 · Depart 06:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day23

Livorno
Arrive 08:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day24At sea
- Day25

Monte-Carlo
Arrive 08:00 · Depart 22:00
The seafront quarter of Monaco on the French Riviera, set on a rocky terrace above the Mediterranean. It is known for the belle-époque Casino, the Hôtel de Paris and the harbour that hosts the Monaco Grand Prix each spring.
- Casino de Monte-Carlo
- Port Hercule
- Grand Prix circuit
- Day26

Villefranche-sur-Mer
Arrive 08:00 · Depart 20:00
A deep-water bay on the French Riviera between Nice and Monaco, framed by steep pastel hillsides. The sheltered harbour is a classic tender anchorage, with a baroque old town behind the waterfront and easy connections along the coast to Nice and Monte Carlo.
- Old town
- Riviera coast
- Nice & Monaco access
- Day27

Marseille
Arrive 08:00 · Depart 21:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day28

Palamós
Arrive 08:00 · Depart 19:00
A fishing town and marina on Spain's Costa Brava, north of Barcelona in Catalonia. Its working harbour and old quarter back onto a curve of beach, while the rocky coves and pine-clad coastline of the region stretch in both directions from the port.
- Costa Brava coves
- Town beach
- Fishing harbour
- Day29

Barcelona
Arrive 06:00 · Depart 06:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day30

Valencia
Arrive 07:30 · Depart 22:00
Spain's third city, on the Mediterranean coast where the old riverbed has become a long ribbon of parkland. It is the birthplace of paella, home to the silk-era Lonja trading hall and to Calatrava's white City of Arts and Sciences complex.
- City of Arts and Sciences
- La Lonja
- Paella
- Day31

Cartagena
Arrive 11:00 · Depart 18:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day32

Málaga
Arrive 08:00 · Depart 22:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day33

Gibraltar
Arrive 07:00 · Depart 18:00
A British territory at the southern tip of Spain, dominated by its towering limestone Rock. Cable cars climb to the summit, home to Europe's only wild monkeys, with sweeping views across the strait toward the coast of Africa.
- The Rock
- Barbary macaques
- St. Michael's Cave
- Day34

Seville
Arrive 11:00 · Depart 21:00
Andalusia's historic capital, reached by river barge up the Guadalquivir in southern Spain. The vast Gothic cathedral, the Moorish Alcázar palace and the dancing of flamenco define a city once enriched by trade with the New World.
- Seville Cathedral
- Royal Alcázar
- Flamenco
- Day35At sea
- Day36At sea
- Day37At sea
- Day38

Lisbon
Arrive 08:00 · Depart 08:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day39

Lisbon
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
Upcoming departures
- 9 Oct 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
38-Night Mediterranean Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 38-night Mediterranean cruise calls at Piraeus, Syros, Pátmos, Marmaris, Rhodes, Agios Nikólaos, Kríti, Santorini, Mykonos, Bodrum, Heraklion (Iraklion), Crete, Alexandria, Valletta, Siracusa, Sicily, Catania, Salerno, Civitavecchia, Livorno, Monte-Carlo, Villefranche-sur-Mer, Marseille, Palamós, Barcelona, Valencia, Cartagena, Málaga, Gibraltar, Seville and Lisbon.
How many days are spent at sea?
9 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Lisbon.
How long is this cruise?
38 nights aboard Azamara Onward.
When does this itinerary sail?
Upcoming departures include 9 Oct 2027. A NestCruise advisor can confirm current availability.