

Cruise itinerary
11-Night Europe Cruise from Istanbul
11 nights · Europe · 12 ports of call
11-night Europe cruise aboard Oceania Nautica, departing Istanbul and calling at Kavala, Thessaloníki, Vólos, Ephesus, Rhodes and Santorini and 5 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Nautica
- Cruise line
- Oceania Cruises
- Duration
- 11 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Istanbul
- Returns
- Civitavecchia
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Nautica sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Istanbul
Depart 18:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day2

Kavala
Arrive 12:00 · Depart 21:00
- Day3

Thessaloníki
Arrive 09:00 · Depart 20:00
Greece's second city, a port on the Thermaic Gulf in the north with a long Byzantine and Ottoman past. The seafront White Tower, Roman-era Rotunda and Arch of Galerius, and a celebrated food scene of mezedes mark the waterfront.
- White Tower
- Rotunda
- Roman Forum
- Day4

Vólos
Arrive 07:00 · Depart 18:00
A coastal city on the Pagasetic Gulf in central Greece, ringed by the wooded slopes of Mount Pelion. A seafront promenade lines the waterfront, and the surrounding mountain villages and beaches are reached by a scenic road up the peninsula.
- Pelion villages
- Seafront promenade
- Tsipouro tavernas
- Day5

Ephesus
Arrive 10:00 · Depart 17:00
- Day6

Rhodes
Arrive 08:00 · Depart 15:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day7

Santorini
Arrive 08:00 · Depart 18:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day8
At Sea
- Day9

Valletta
Arrive 08:00 · Depart 22:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day10

Siracuse, Sicily
Arrive 08:00 · Depart 18:00
A historic city on the southeast coast of Sicily, once among the greatest powers of the ancient Greek world. The island of Ortigia holds its baroque core and a temple-turned-cathedral, beside a vast archaeological park with a Greek theatre.
- Ortigia island
- Greek theatre
- Baroque cathedral
- Day11

Salerno
Arrive 10:00 · Depart 17:00
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day12

Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
Upcoming departures
- 16 Jun 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
11-Night Europe Cruise from Istanbul FAQ
Which ports does this cruise visit?
This 11-night Europe cruise calls at Istanbul, Kavala, Thessaloníki, Vólos, Ephesus, Rhodes, Santorini, At Sea, Valletta, Siracuse, Sicily, Salerno and Civitavecchia.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Istanbul and ends in Civitavecchia.
How long is this cruise?
11 nights aboard Oceania Nautica.
When does this itinerary sail?
Upcoming departures include 16 Jun 2027. A NestCruise advisor can confirm current availability.