

Cruise itinerary
20-Night World Cruise Cruise from Santos
20 nights · World Cruise · 10 ports of call
20-night World Cruise cruise aboard MSC Virtuosa, departing Santos and calling at Rio de Janeiro, Buzios, Salvador de Bahia, Maceió, Santa Cruz de Tenerife and Tangier and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Virtuosa
- Cruise line
- MSC Cruises
- Duration
- 20 nights
- Region
- World Cruise
- Departs
- Santos
- Returns
- Palermo
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Virtuosa sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Santos
Depart 18:00
Brazil's busiest port, on the coast of São Paulo state and the main gateway to that vast city. Its waterfront sits below green coastal hills, with historic coffee-trade buildings, an aquarium and long urban beaches backed by a seafront garden.
- Coffee Museum
- Santos beach gardens
- Pelé Museum
- Day2

Rio de Janeiro
Arrive 09:00 · Depart 19:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day3

Buzios
Arrive 07:00 · Depart 18:00
A chic beach resort on a rocky peninsula east of Rio de Janeiro, Brazil, once a fishing village made famous by Brigitte Bardot. Some two dozen beaches ring the headland, with a cobbled centre, a sailing harbour and the Orla Bardot promenade.
- Geribá Beach
- Rua das Pedras
- Orla Bardot
- Day4At sea
- Day5

Salvador de Bahia
Arrive 09:00 · Depart 19:00
Brazil's first colonial capital, set on a bluff above the Bay of All Saints. The cobbled Pelourinho district holds pastel baroque churches and the rhythms of Afro-Brazilian culture, with capoeira, candomblé and acarajé stalls woven into daily life.
- Pelourinho
- Elevador Lacerda
- Acarajé
- Day6At sea
- Day7

Maceió
Arrive 07:00 · Depart 17:00
The capital of Alagoas on Brazil's north-east coast, fringed by white sand and warm reef-protected lagoons. Pajuçara and Ponta Verde beaches draw swimmers, and jangada rafts carry visitors out to the natural tidal pools offshore.
- Pajuçara beach
- Natural pools
- Jangada rafts
- Day8At sea
- Day9At sea
- Day10At sea
- Day11At sea
- Day12At sea
- Day13At sea
- Day14

Santa Cruz de Tenerife
Arrive 07:00 · Depart 17:00
The capital of Tenerife in Spain's Canary Islands, a volcanic Atlantic port off northwest Africa. Santa Cruz is known for its sail-shaped Auditorio concert hall, the palm-lined Plaza de España, and the road up to Mount Teide, Spain's highest peak.
- Auditorio de Tenerife
- Mount Teide
- Plaza de España
- Day15At sea
- Day16

Tangier
Arrive 08:00 · Depart 19:00
A Moroccan port at the mouth of the Strait of Gibraltar, where the Atlantic meets the Mediterranean and Europe lies in view across the water. Its walled medina and kasbah climb above the harbour, long a meeting point of African, Arab and European worlds.
- The Medina
- Kasbah
- Strait of Gibraltar
- Day17At sea
- Day18

Barcelona
Arrive 07:00 · Depart 19:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day19At sea
- Day20

La Goulette
Arrive 08:00 · Depart 18:00
The port of Tunis on the Gulf of Tunis in Tunisia, the usual landing for ships calling at the capital. The ancient ruins of Carthage and the blue-and-white clifftop village of Sidi Bou Saïd lie close by, with the city's great walled medina a short drive away.
- Carthage ruins
- Sidi Bou Saïd
- Tunis medina
- Day21

Palermo
Arrive 08:00
The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
- Cappella Palatina
- Ballarò market
- Monreale mosaics
Upcoming departures
- 3 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
20-Night World Cruise Cruise from Santos FAQ
Which ports does this cruise visit?
This 20-night World Cruise cruise calls at Santos, Rio de Janeiro, Buzios, Salvador de Bahia, Maceió, Santa Cruz de Tenerife, Tangier, Barcelona, La Goulette and Palermo.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Santos and ends in Palermo.
How long is this cruise?
20 nights aboard MSC Virtuosa.
When does this itinerary sail?
Upcoming departures include 3 Apr 2027. A NestCruise advisor can confirm current availability.