

Cruise itinerary
25-Night World Cruise Cruise from Civitavecchia
25 nights · World Cruise · 12 ports of call
25-night World Cruise cruise aboard MSC Sinfonia, departing Civitavecchia and calling at Messina, Rhodes, Limassol, Alexandria, Suez Canal (transit), Egypt and Sharm El Sheikh and 5 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Sinfonia
- Cruise line
- MSC Cruises
- Duration
- 25 nights
- Region
- World Cruise
- Departs
- Civitavecchia
- Returns
- Durban
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Sinfonia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Civitavecchia
Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2

Messina
Arrive 12:00 · Depart 17:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day3At sea
- Day4

Rhodes
Arrive 08:00 · Depart 16:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day5

Limassol
Arrive 09:00 · Depart 15:00
A southern coastal city on Cyprus in the eastern Mediterranean, set around a long seafront promenade. A medieval castle anchors the old town, and the port is a base for the ancient ruins of Kourion and the wine villages of the Troodos foothills.
- Limassol Castle
- Kourion ruins
- seafront promenade
- Day6

Alexandria
Arrive 08:00 · Depart 23:00
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day7
Suez Canal (transit), Egypt
Arrive 22:30 · Depart 23:00
- Day8
Suez Canal (transit), Egypt
Arrive 16:30 · Depart 17:00
- Day9

Sharm El Sheikh
Arrive 08:00 · Depart 19:00
- Day10

Safaga
Arrive 06:00 · Depart 21:00
A Red Sea port on Egypt's eastern coast, ringed by desert and coral reefs. It serves mainly as the sea gateway to the temples of Luxor and the Valley of the Kings on the Nile, a long inland drive away, while its own shore is known for diving and snorkelling.
- gateway to Luxor
- Red Sea reefs
- Valley of the Kings
- Day11At sea
- Day12At sea
- Day13At sea
- Day14At sea
- Day15At sea
- Day16At sea
- Day17At sea
- Day18

Port Victoria
Arrive 07:00 · Depart 18:00
- Day19At sea
- Day20At sea
- Day21

Port Louis
Arrive 09:00 · Depart 18:00
The capital and main port of Mauritius, set on a natural harbour beneath a backdrop of jagged peaks in the Indian Ocean. A multicultural city, it is known for its colonial Caudan waterfront, the crowded stalls of the Central Market and the racecourse at the Champ de Mars.
- Caudan Waterfront
- Central Market
- Champ de Mars
- Day22

Possession
Arrive 09:00 · Depart 18:00
- Day23At sea
- Day24At sea
- Day25At sea
- Day26

Durban
Arrive 07:00
South Africa's largest port and a subtropical city on the Indian Ocean coast. Known for its warm beaches along the Golden Mile, a strong Zulu and Indian heritage, and as a gateway to the Drakensberg mountains and the game reserves of KwaZulu-Natal.
- Golden Mile beaches
- uShaka Marine World
- Victoria Street Market
Upcoming departures
- 18 Oct 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
25-Night World Cruise Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 25-night World Cruise cruise calls at Civitavecchia, Messina, Rhodes, Limassol, Alexandria, Suez Canal (transit), Egypt, Sharm El Sheikh, Safaga, Port Victoria, Port Louis, Possession and Durban.
How many days are spent at sea?
13 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Durban.
How long is this cruise?
25 nights aboard MSC Sinfonia.
When does this itinerary sail?
Upcoming departures include 18 Oct 2027. A NestCruise advisor can confirm current availability.