Cruise itinerary
12-Night Europe Cruise from Genoa
12 nights · Europe · 6 ports of call
12-night Europe cruise aboard MSC Sinfonia, departing Genoa and calling at Livorno, Civitavecchia, Valencia, Barcelona and Marseille.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Sinfonia
- Cruise line
- MSC Cruises
- Duration
- 12 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Genoa
- Returns
- Genoa
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Sinfonia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Genoa
Depart 19:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day2
Livorno
Arrive 07:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day3
Civitavecchia
Arrive 07:00 · Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day4At sea
- Day5
Valencia
Arrive 07:00 · Depart 21:00
Spain's third city, on the Mediterranean coast where the old riverbed has become a long ribbon of parkland. It is the birthplace of paella, home to the silk-era Lonja trading hall and to Calatrava's white City of Arts and Sciences complex.
- City of Arts and Sciences
- La Lonja
- Paella
- Day6
Barcelona
Arrive 09:00 · Depart 18:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day7
Marseille
Arrive 08:00 · Depart 16:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day8
Livorno
Arrive 08:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day9
Civitavecchia
Arrive 07:00 · Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day10At sea
- Day11
Valencia
Arrive 07:00 · Depart 21:00
Spain's third city, on the Mediterranean coast where the old riverbed has become a long ribbon of parkland. It is the birthplace of paella, home to the silk-era Lonja trading hall and to Calatrava's white City of Arts and Sciences complex.
- City of Arts and Sciences
- La Lonja
- Paella
- Day12At sea
- Day13
Genoa
Arrive 08:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
Upcoming departures
- 6 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Europe Cruise from Genoa FAQ
Which ports does this cruise visit?
This 12-night Europe cruise calls at Genoa, Livorno, Civitavecchia, Valencia, Barcelona and Marseille.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Genoa.
How long is this cruise?
12 nights aboard MSC Sinfonia.
When does this itinerary sail?
Upcoming departures include 6 Apr 2027. A NestCruise advisor can confirm current availability.