

Cruise itinerary
29-Night Caribbean Cruise from Miami, Florida
29 nights · Caribbean · 13 ports of call
29-night Caribbean cruise aboard MSC Poesia, departing Miami, Florida and calling at Ocho Rios, Cartagena, Colón, Puerto Limón, Roatán Island and Belize City and 6 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Poesia
- Cruise line
- MSC Cruises
- Duration
- 29 nights
- Region
- Caribbean · Americas · South America · World Cruise
- Departs
- Miami, Florida
- Returns
- Seattle, Washington
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Poesia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Miami, Florida
Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2At sea
- Day3

Ocho Rios
Arrive 09:00 · Depart 18:00
A resort town on Jamaica's north coast, set among green hills and a string of beaches. The terraced cascades of Dunn's River Falls are the headline attraction, with botanical gardens, river tubing and reggae-filled markets close to the cruise pier.
- Dunn's River Falls
- Resort beaches
- Botanical gardens
- Day4At sea
- Day5

Cartagena
Arrive 07:00 · Depart 17:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day6

Colón
Arrive 10:00 · Depart 20:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day7

Puerto Limón
Arrive 07:00 · Depart 18:00
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day8At sea
- Day9

Roatán Island
Arrive 08:00 · Depart 18:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day10

Belize City
Arrive 07:00 · Depart 15:00
The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
- Barrier reef
- Maya ruins
- Cave tubing
- Day11At sea
- Day12

Miami, Florida
Arrive 07:00 · Depart 18:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day13At sea
- Day14At sea
- Day15

Cartagena
Arrive 07:00 · Depart 17:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day16
Cruising Panama Canal
Arrive 09:00 · Depart 06:15

Colón
Arrive 18:00 · Depart 19:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day17
Cruising Panama Canal
Arrive 06:00 · Depart 18:15
- Day18At sea
- Day19At sea
- Day20

Huatulco (Santa María Huatulco)
Arrive 10:00 · Depart 20:00
- Day21At sea
- Day22At sea
- Day23

Cabo San Lucas
Arrive 07:00 · Depart 14:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day24At sea
- Day25

San Diego, California
Arrive 07:00 · Depart 20:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day26

Los Angeles, California
Arrive 07:00 · Depart 21:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day27At sea
- Day28At sea
- Day29At sea
- Day30

Seattle, Washington
Arrive 07:00
A port city in Washington State on Puget Sound, framed by Mount Rainier and the Olympic Mountains. Seattle is a major gateway to Alaska cruises, known for Pike Place Market, the Space Needle, and the original Starbucks near the waterfront.
- Pike Place Market
- Space Needle
- Puget Sound
Upcoming departures
- 28 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
29-Night Caribbean Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 29-night Caribbean cruise calls at Miami, Florida, Ocho Rios, Cartagena, Colón, Puerto Limón, Roatán Island, Belize City, Cruising Panama Canal, Huatulco (Santa María Huatulco), Cabo San Lucas, San Diego, California, Los Angeles, California and Seattle, Washington.
How many days are spent at sea?
15 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Seattle, Washington.
How long is this cruise?
29 nights aboard MSC Poesia.
When does this itinerary sail?
Upcoming departures include 28 Mar 2027. A NestCruise advisor can confirm current availability.