MSC Poesia — 25-Night World Cruise Cruise from Miami, Florida

Cruise itinerary

25-Night World Cruise Cruise from Miami, Florida

25 nights · World Cruise · 14 ports of call

25-night World Cruise cruise aboard MSC Poesia, departing Miami, Florida and calling at Cartagena, Colón, Cruising Panama Canal, Huatulco (Santa María Huatulco), Cabo San Lucas and San Diego, California and 7 more.

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At a glance

Ship: MSC Poesia
Cruise line: MSC Cruises
Duration: 25 nights
Region: World Cruise
Departs: Miami, Florida
Returns: Seattle, Washington

How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Poesia sailing, typically within 24 hours.

Where this voyage takes you

Voyage route — calls shown in order; map is schematic.

Day-by-day itinerary

Day
1
- Miami, Florida
  Depart 18:00
  The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
  - South Beach
  - Little Havana
  - Wynwood murals
Day
2
At sea
Day
3
At sea
Day
4
- Cartagena
  Arrive 07:00 · Depart 17:00
  A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
  - Walled old town
  - San Felipe fortress
  - Plaza Santo Domingo
Day
5
- Colón
  Arrive 09:00 · Depart 19:00
  A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
  - Gatún Locks
  - Panama Canal
  - Portobelo forts
Day
6
- Cruising Panama Canal
  Arrive 06:00 · Depart 06:15
- Cruising Panama Canal
  Arrive 18:00 · Depart 18:15
Day
7
At sea
Day
8
At sea
Day
9
- Huatulco (Santa María Huatulco)
  Arrive 10:00 · Depart 20:00
Day
10
At sea
Day
11
At sea
Day
12
- Cabo San Lucas
  Arrive 07:00 · Depart 14:00
  A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
  - El Arco
  - Lover's Beach
  - Cabo marina
Day
13
At sea
Day
14
- San Diego, California
  Arrive 07:00 · Depart 20:00
  A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
  - Balboa Park
  - Gaslamp Quarter
  - San Diego Zoo
Day
15
- Los Angeles, California
  Arrive 07:00 · Depart 21:00
  The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
  - Hollywood
  - Santa Monica Pier
  - Getty Center
Day
16
At sea
Day
17
At sea
Day
18
At sea
Day
19
- Seattle, Washington
  Arrive 07:00 · Depart 17:00
  A port city in Washington State on Puget Sound, framed by Mount Rainier and the Olympic Mountains. Seattle is a major gateway to Alaska cruises, known for Pike Place Market, the Space Needle, and the original Starbucks near the waterfront.
  - Pike Place Market
  - Space Needle
  - Puget Sound
Day
20
At sea
Day
21
- Ketchikan, Alaska
  Arrive 07:00 · Depart 17:00
  A southeast Alaska town built on stilts and boardwalks along the Tongass Narrows, long a centre of the salmon trade. It is known for the world's largest collection of totem poles and the historic boardwalk over Ketchikan Creek at Creek Street.
  - Creek Street
  - Totem poles
  - Tongass Narrows
Day
22
- Icy Strait Point
  Arrive 10:00 · Depart 19:00
  A private cruise destination near the Tlingit village of Hoonah on Chichagof Island in Southeast Alaska, built around a restored 1930s salmon cannery. Forested trails, whale-rich waters and one of the world's longest ziplines draw visitors, with Glacier Bay close by.
  - Restored cannery
  - Whale watching
  - ZipRider zipline
Day
23
- Cruising Tracy Arm Fjord Alaska
  Arrive 07:00 · Depart 07:30
- Juneau, Alaska
  Arrive 14:00 · Depart 22:00
  Alaska's capital, reachable only by sea or air, hemmed between steep forested mountains and the Gastineau Channel. The Mendenhall Glacier sits just outside town, tramway cars climb Mount Roberts, and gold-rush history lines the downtown streets.
  - Mendenhall Glacier
  - Mount Roberts Tramway
  - Gastineau Channel
Day
24
At sea
Day
25
- Victoria, British Columbia
  Arrive 20:00 · Depart 23:59
  The capital of British Columbia, set on the southern tip of Vancouver Island in Canada. The Inner Harbour is framed by the ivy-clad Empress Hotel and the domed Parliament Buildings, with whale-watching boats and Butchart Gardens close at hand.
  - Inner Harbour
  - Butchart Gardens
  - Empress Hotel
Day
26
- Seattle, Washington
  Arrive 07:00
  A port city in Washington State on Puget Sound, framed by Mount Rainier and the Olympic Mountains. Seattle is a major gateway to Alaska cruises, known for Pike Place Market, the Space Needle, and the original Starbucks near the waterfront.
  - Pike Place Market
  - Space Needle
  - Puget Sound

Upcoming departures

8 Apr 2027

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

25-Night World Cruise Cruise from Miami, Florida FAQ

Which ports does this cruise visit?

This 25-night World Cruise cruise calls at Miami, Florida, Cartagena, Colón, Cruising Panama Canal, Huatulco (Santa María Huatulco), Cabo San Lucas, San Diego, California, Los Angeles, California, Seattle, Washington, Ketchikan, Alaska, Icy Strait Point, Cruising Tracy Arm Fjord Alaska, Juneau, Alaska and Victoria, British Columbia.

How many days are spent at sea?

13 days are spent at sea; the rest are in port.

Where does this cruise depart from?

It departs from Miami, Florida and ends in Seattle, Washington.

How long is this cruise?

25 nights aboard MSC Poesia.

When does this itinerary sail?

Upcoming departures include 8 Apr 2027. A NestCruise advisor can confirm current availability.

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About: MSC Poesia — 25-Night World Cruise Cruise from Miami, Florida

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