Cruise itinerary
24-Night World Cruise Cruise from Seattle, Washington
24 nights · World Cruise · 11 ports of call
24-night World Cruise cruise aboard MSC Poesia, departing Seattle, Washington and calling at Los Angeles, California, San Diego, California, Cabo San Lucas, Puntarenas, Cruising Panama Canal and Colón and 4 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Poesia
- Cruise line
- MSC Cruises
- Duration
- 24 nights
- Region
- World Cruise
- Departs
- Seattle, Washington
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Poesia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Seattle, Washington
Depart 18:00
A port city in Washington State on Puget Sound, framed by Mount Rainier and the Olympic Mountains. Seattle is a major gateway to Alaska cruises, known for Pike Place Market, the Space Needle, and the original Starbucks near the waterfront.
- Pike Place Market
- Space Needle
- Puget Sound
- Day2At sea
- Day3At sea
- Day4At sea
- Day5
Los Angeles, California
Arrive 07:00 · Depart 21:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day6
San Diego, California
Arrive 08:00 · Depart 18:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day7At sea
- Day8At sea
- Day9
Cabo San Lucas
Arrive 07:00 · Depart 16:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day10At sea
- Day11At sea
- Day12At sea
- Day13
Puntarenas
Arrive 10:00 · Depart 20:00
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day14At sea
- Day15
Cruising Panama Canal
Arrive 09:00 · Depart 09:15
Cruising Panama Canal
Arrive 21:00 · Depart 21:15
- Day16
Colón
Arrive 07:00 · Depart 19:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day17
Cartagena
Arrive 11:00 · Depart 18:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day18At sea
- Day19At sea
- Day20
Miami, Florida
Arrive 07:00 · Depart 19:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day21At sea
- Day22
Georgetown, Grand Cayman
Arrive 08:00 · Depart 18:00
Grand Cayman's capital and the main port of the Cayman Islands, set on the calm western shore. Cruise ships tender into the harbour beside Seven Mile Beach, with Stingray City sandbars and Caribbean reef diving a short boat ride away.
- Seven Mile Beach
- Stingray City
- Seven Mile reefs
- Day23
Ocho Rios
Arrive 08:00 · Depart 17:00
A resort town on Jamaica's north coast, set among green hills and a string of beaches. The terraced cascades of Dunn's River Falls are the headline attraction, with botanical gardens, river tubing and reggae-filled markets close to the cruise pier.
- Dunn's River Falls
- Resort beaches
- Botanical gardens
- Day24At sea
- Day25
Miami, Florida
Arrive 07:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 28 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
24-Night World Cruise Cruise from Seattle, Washington FAQ
Which ports does this cruise visit?
This 24-night World Cruise cruise calls at Seattle, Washington, Los Angeles, California, San Diego, California, Cabo San Lucas, Puntarenas, Cruising Panama Canal, Colón, Cartagena, Miami, Florida, Georgetown, Grand Cayman and Ocho Rios.
How many days are spent at sea?
14 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Seattle, Washington and ends in Miami, Florida.
How long is this cruise?
24 nights aboard MSC Poesia.
When does this itinerary sail?
Upcoming departures include 28 Sep 2026. A NestCruise advisor can confirm current availability.