MSC Poesia — 21-Night Caribbean Cruise from Miami, Florida

Cruise itinerary

21-Night Caribbean Cruise from Miami, Florida

21 nights · Caribbean · 11 ports of call

21-night Caribbean cruise aboard MSC Poesia, departing Miami, Florida and calling at Kralendijk, Oranjestad, Willemstad, Cabo Rojo, Ocho Rios and Cartagena and 4 more.

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At a glance

Ship: MSC Poesia
Cruise line: MSC Cruises
Duration: 21 nights
Region: Caribbean · Americas · South America
Departs: Miami, Florida
Returns: Miami, Florida

How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Poesia sailing, typically within 24 hours.

Where this voyage takes you

Voyage route — calls shown in order; map is schematic.

Day-by-day itinerary

Day
1
- Miami, Florida
  Depart 17:00
  The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
  - South Beach
  - Little Havana
  - Wynwood murals
Day
2
At sea
Day
3
At sea
Day
4
- Kralendijk
  Arrive 08:00 · Depart 18:00
  The capital of Bonaire, a Dutch-Caribbean island known above all for diving and snorkelling along its protected fringing reef. The small waterfront town keeps pastel Dutch-colonial facades, with salt pans and flamingo flats lying to the south.
  - Bonaire reef diving
  - Salt pans
  - Flamingo flats
Day
5
- Oranjestad
  Arrive 08:00 · Depart 18:00
  The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
  - Eagle Beach
  - Palm Beach
  - Dutch colonial centre
Day
6
- Willemstad
  Arrive 08:00 · Depart 18:00
  The capital of Curaçao in the southern Caribbean, with a UNESCO-listed centre of Dutch colonial architecture. Willemstad is known for the candy-coloured waterfront of Handelskade, the swinging Queen Emma pontoon bridge, and its floating market.
  - Handelskade façades
  - Queen Emma Bridge
  - Floating Market
Day
7
At sea
Day
8
- Cabo Rojo
  Arrive 07:00 · Depart 15:30
  A remote stretch of the Dominican Republic's far southwest, near the Pedernales frontier with Haiti. The wider region is known for the turquoise water of Bahía de las Águilas and the arid Jaragua National Park.
  - Bahía de las Águilas
  - Jaragua park
  - Caribbean coast
Day
9
- Ocho Rios
  Arrive 08:00 · Depart 16:00
  A resort town on Jamaica's north coast, set among green hills and a string of beaches. The terraced cascades of Dunn's River Falls are the headline attraction, with botanical gardens, river tubing and reggae-filled markets close to the cruise pier.
  - Dunn's River Falls
  - Resort beaches
  - Botanical gardens
Day
10
At sea
Day
11
- Miami, Florida
  Arrive 07:00 · Depart 17:00
  The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
  - South Beach
  - Little Havana
  - Wynwood murals
Day
12
At sea
Day
13
- Ocho Rios
  Arrive 09:00 · Depart 18:00
  A resort town on Jamaica's north coast, set among green hills and a string of beaches. The terraced cascades of Dunn's River Falls are the headline attraction, with botanical gardens, river tubing and reggae-filled markets close to the cruise pier.
  - Dunn's River Falls
  - Resort beaches
  - Botanical gardens
Day
14
At sea
Day
15
- Cartagena
  Arrive 07:00 · Depart 17:00
  A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
  - Walled old town
  - San Felipe fortress
  - Plaza Santo Domingo
Day
16
- Colón
  Arrive 10:00 · Depart 20:00
  A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
  - Gatún Locks
  - Panama Canal
  - Portobelo forts
Day
17
- Puerto Limón
  Arrive 07:00 · Depart 18:00
  A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
  - Tortuguero canals
  - Rainforest wildlife
  - Banana country
Day
18
At sea
Day
19
- Roatán Island
  Arrive 08:00 · Depart 18:00
  An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
  - West Bay Beach
  - Barrier reef diving
  - West End
Day
20
- Belize City
  Arrive 07:00 · Depart 15:00
  The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
  - Barrier reef
  - Maya ruins
  - Cave tubing
Day
21
At sea
Day
22
- Miami, Florida
  Arrive 07:00
  The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
  - South Beach
  - Little Havana
  - Wynwood murals

Upcoming departures

22 Oct 2026
1 Nov 2026
12 Nov 2026
22 Nov 2026
13 Dec 2026
3 Jan 2027

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

21-Night Caribbean Cruise from Miami, Florida FAQ

Which ports does this cruise visit?

This 21-night Caribbean cruise calls at Miami, Florida, Kralendijk, Oranjestad, Willemstad, Cabo Rojo, Ocho Rios, Cartagena, Colón, Puerto Limón, Roatán Island and Belize City.

How many days are spent at sea?

8 days are spent at sea; the rest are in port.

Where does this cruise depart from?

It is a round-trip sailing from Miami, Florida.

How long is this cruise?

21 nights aboard MSC Poesia.

When does this itinerary sail?

Upcoming departures include 22 Oct 2026, 1 Nov 2026, 12 Nov 2026 and 22 Nov 2026. A NestCruise advisor can confirm current availability.

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About: MSC Poesia — 21-Night Caribbean Cruise from Miami, Florida

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