

Cruise itinerary
5-Night Europe Cruise from Lisbon
5 nights · Europe · 5 ports of call
5-night Europe cruise aboard MSC Opera, departing Lisbon and calling at Alicante, Mahón, Menorca, Olbia and Genoa.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Opera
- Cruise line
- MSC Cruises
- Duration
- 5 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Lisbon
- Returns
- Genoa
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Opera sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Lisbon
Depart 18:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day2At sea
- Day3

Alicante
Arrive 09:00 · Depart 17:00
A sun-warmed port on Spain's Costa Blanca, set below the Santa Bárbara castle on its rocky headland. The palm-lined Explanada promenade leads to a long city beach, with the old Barrio Santa Cruz climbing the hill in white houses.
- Santa Bárbara Castle
- Explanada promenade
- Postiguet Beach
- Day4

Mahón, Menorca
Arrive 09:00 · Depart 16:00
The harbour capital of Menorca in Spain's Balearic Islands, set at the head of one of the Mediterranean's deepest natural inlets. Georgian touches from a British period linger in the old town, while quiet coves and prehistoric stone sites lie across the island.
- Port of Maó
- Fortalesa de la Mola
- Gin Xoriguer
- Day5

Olbia
Arrive 10:00 · Depart 19:00
A port town on the northeast coast of Sardinia, set on a sheltered gulf and serving as the gateway to the Costa Smeralda. The surrounding coast is known for granite headlands and turquoise coves, while the old centre keeps Roman and medieval roots.
- Costa Smeralda
- San Simplicio basilica
- Granite coves
- Day6

Genoa
Arrive 09:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
Upcoming departures
- 5 Oct 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
5-Night Europe Cruise from Lisbon FAQ
Which ports does this cruise visit?
This 5-night Europe cruise calls at Lisbon, Alicante, Mahón, Menorca, Olbia and Genoa.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Lisbon and ends in Genoa.
How long is this cruise?
5 nights aboard MSC Opera.
When does this itinerary sail?
Upcoming departures include 5 Oct 2026. A NestCruise advisor can confirm current availability.