Cruise itinerary
10-Night Mediterranean Cruise from Genoa
10 nights · Mediterranean · 8 ports of call
10-night Mediterranean cruise aboard MSC Opera, departing Genoa and calling at Marseille, Málaga, Cádiz, Lisbon, Alicante and Port-Vendres and 1 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Opera
- Cruise line
- MSC Cruises
- Duration
- 10 nights
- Region
- Mediterranean
- Departs
- Genoa
- Returns
- Genoa
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Opera sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Genoa
Depart 18:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day2
Marseille
Arrive 09:00 · Depart 17:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day3At sea
- Day4
Málaga
Arrive 08:00 · Depart 18:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day5
Cádiz
Arrive 07:00 · Depart 17:00
One of the oldest continuously inhabited cities in Western Europe, set on a narrow spit almost surrounded by the Atlantic in Spain's Andalusia. A gold-domed cathedral rises over the old town's tight lanes, sea walls and the long sands of La Caleta.
- Cádiz Cathedral
- La Caleta beach
- Old town lanes
- Day6
Lisbon
Arrive 09:00 · Depart 18:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day7At sea
- Day8
Alicante
Arrive 09:00 · Depart 17:00
A sun-warmed port on Spain's Costa Blanca, set below the Santa Bárbara castle on its rocky headland. The palm-lined Explanada promenade leads to a long city beach, with the old Barrio Santa Cruz climbing the hill in white houses.
- Santa Bárbara Castle
- Explanada promenade
- Postiguet Beach
- Day9
Port-Vendres
Arrive 09:00 · Depart 16:00
- Day10
Olbia
Arrive 10:00 · Depart 19:00
A port town on the northeast coast of Sardinia, set on a sheltered gulf and serving as the gateway to the Costa Smeralda. The surrounding coast is known for granite headlands and turquoise coves, while the old centre keeps Roman and medieval roots.
- Costa Smeralda
- San Simplicio basilica
- Granite coves
- Day11
Genoa
Arrive 09:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
Upcoming departures
- 23 May 2026
- 2 Jun 2026
- 12 Jun 2026
- 22 Jun 2026
- 2 Jul 2026
- 12 Jul 2026
- 22 Jul 2026
- 1 Aug 2026
- 11 Aug 2026
- 21 Aug 2026
- 31 Aug 2026
- 10 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Mediterranean Cruise from Genoa FAQ
Which ports does this cruise visit?
This 10-night Mediterranean cruise calls at Genoa, Marseille, Málaga, Cádiz, Lisbon, Alicante, Port-Vendres and Olbia.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Genoa.
How long is this cruise?
10 nights aboard MSC Opera.
When does this itinerary sail?
Upcoming departures include 23 May 2026, 2 Jun 2026, 12 Jun 2026 and 22 Jun 2026. A NestCruise advisor can confirm current availability.