Cruise itinerary
21-Night World Cruise Cruise from Santos
21 nights · World Cruise · 11 ports of call
21-night World Cruise cruise aboard MSC Musica, departing Santos and calling at Rio de Janeiro, Maceió, Las Palmas de Gran Canaria, Tarragona, Marseille and Genoa and 4 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Musica
- Cruise line
- MSC Cruises
- Duration
- 21 nights
- Region
- World Cruise
- Departs
- Santos
- Returns
- Valencia
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Musica sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Santos
Depart 18:00
Brazil's busiest port, on the coast of São Paulo state and the main gateway to that vast city. Its waterfront sits below green coastal hills, with historic coffee-trade buildings, an aquarium and long urban beaches backed by a seafront garden.
- Coffee Museum
- Santos beach gardens
- Pelé Museum
- Day2
Rio de Janeiro
Arrive 07:00 · Depart 18:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day3At sea
- Day4At sea
- Day5
Maceió
Arrive 07:00 · Depart 16:00
The capital of Alagoas on Brazil's north-east coast, fringed by white sand and warm reef-protected lagoons. Pajuçara and Ponta Verde beaches draw swimmers, and jangada rafts carry visitors out to the natural tidal pools offshore.
- Pajuçara beach
- Natural pools
- Jangada rafts
- Day6At sea
- Day7At sea
- Day8At sea
- Day9At sea
- Day10At sea
- Day11At sea
- Day12
Las Palmas de Gran Canaria
Arrive 07:00 · Depart 17:00
The largest city of the Canary Islands, on Gran Canaria off the African coast. A long city beach curves beside the port, and the historic Vegueta quarter holds the cathedral and the house where Columbus is said to have stayed.
- Las Canteras Beach
- Vegueta quarter
- Columbus House
- Day13At sea
- Day14At sea
- Day15
Tarragona
Arrive 09:00 · Depart 18:00
A coastal city in Catalonia, northeast Spain, built on the site of a major Roman provincial capital. Its amphitheatre, forum and aqueduct survive among the old town's medieval lanes, with a long Mediterranean beach below the upper town.
- Roman amphitheatre
- Tarragona Cathedral
- Les Ferreres Aqueduct
- Day16
Marseille
Arrive 08:00 · Depart 17:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day17
Genoa
Arrive 08:00 · Depart 17:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day18
Civitavecchia
Arrive 08:00 · Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day19
Palermo
Arrive 11:00 · Depart 20:00
The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
- Cappella Palatina
- Ballarò market
- Monreale mosaics
- Day20At sea
- Day21
Ibiza
Arrive 12:30 · Depart 23:00
A Balearic island in the western Mediterranean off Spain's east coast, known equally for nightlife and quiet coves. Ibiza Town's walled Dalt Vila old quarter rises above the harbour, with sandy beaches and the islet of Es Vedrà to the southwest.
- Dalt Vila
- Es Vedrà
- Beach coves
- Day22
Valencia
Arrive 07:00
Spain's third city, on the Mediterranean coast where the old riverbed has become a long ribbon of parkland. It is the birthplace of paella, home to the silk-era Lonja trading hall and to Calatrava's white City of Arts and Sciences complex.
- City of Arts and Sciences
- La Lonja
- Paella
Upcoming departures
- 1 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night World Cruise Cruise from Santos FAQ
Which ports does this cruise visit?
This 21-night World Cruise cruise calls at Santos, Rio de Janeiro, Maceió, Las Palmas de Gran Canaria, Tarragona, Marseille, Genoa, Civitavecchia, Palermo, Ibiza and Valencia.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Santos and ends in Valencia.
How long is this cruise?
21 nights aboard MSC Musica.
When does this itinerary sail?
Upcoming departures include 1 Apr 2027. A NestCruise advisor can confirm current availability.