Cruise itinerary
31-Night South America Cruise from Fort Lauderdale, Florida
31 nights · South America · 19 ports of call
31-night South America cruise aboard Oosterdam, departing Fort Lauderdale, Florida and calling at Grand Cayman, Panama Canal Transit, Panama City, Manta, Salaverry and Callao and 12 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oosterdam
- Cruise line
- Holland America Line
- Duration
- 31 nights
- Region
- South America
- Departs
- Fort Lauderdale, Florida
- Returns
- Buenos Aires
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Fort Lauderdale, Florida
Depart 17:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day2At sea
- Day3
Grand Cayman
Arrive 10:00 · Depart 18:00
The largest of the Cayman Islands, a low coral island in the western Caribbean and a noted diving and offshore-banking centre. George Town's cruise harbour sits a short ride from Seven Mile Beach and the shallow sandbar of Stingray City.
- Seven Mile Beach
- Stingray City
- George Town
- Day4At sea
- Day5
Panama City
Arrive 21:00 · Depart 16:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day6At sea
- Day7At sea
- Day8
Manta
Arrive 06:00 · Depart 20:00
- Day9At sea
- Day10
Salaverry
Arrive 08:00 · Depart 17:00
- Day11
Callao
Arrive 10:00 · Depart 18:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day12At sea
- Day13
Pisco
Arrive 07:00 · Depart 18:00
- Day14At sea
- Day15At sea
- Day16
Coquimbo
Arrive 08:00 · Depart 16:00
- Day17
San Antonio
Arrive 07:00 · Depart 17:00
- Day18At sea
- Day19
Puerto Montt
Arrive 08:00 · Depart 17:00
A port city in Chile's Lake District, set on the Reloncaví Sound where the central valley meets the fjords of Patagonia. Snow-capped volcanoes ring the bay, and the town is a launch point for trips to lakes, the German-influenced settlement of Puerto Varas and Chiloé island.
- Osorno Volcano
- Puerto Varas
- Angelmó market
- Day20
Puerto Chacabuco
Arrive 11:00 · Depart 20:00
- Day21At sea
- Day22
Chilean Fjords
Arrive 08:00 · Depart 10:00
- Day23At sea
- Day24
Punta Arenas
Arrive 06:00 · Depart 18:00
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day25
Ushuaia
Arrive 12:00 · Depart 20:00
The world's southernmost city, on Argentina's Tierra del Fuego at the tip of South America. Backed by snowy peaks on the Beagle Channel, it is the chief departure port for Antarctica and a base for the Patagonian wilderness.
- Beagle Channel
- Tierra del Fuego park
- End of the world
- Day26
Cape Horn
- Day27
Port Stanley
Arrive 08:00 · Depart 18:00
The small capital of the Falkland Islands in the South Atlantic, a row of brightly painted houses and tin roofs along a sheltered harbour. Penguin colonies and windswept moorland surround the settlement, with Christ Church Cathedral and its whalebone arch at the waterfront.
- Penguin colonies
- Whalebone Arch
- Christ Church Cathedral
- Day28At sea
- Day29At sea
- Day30
Montevideo
Arrive 08:00 · Depart 18:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day31
Buenos Aires
Arrive 08:00 · Depart 08:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day32
Buenos Aires
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
Upcoming departures
- 18 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
31-Night South America Cruise from Fort Lauderdale, Florida FAQ
Which ports does this cruise visit?
This 31-night South America cruise calls at Fort Lauderdale, Florida, Grand Cayman, Panama Canal Transit, Panama City, Manta, Salaverry, Callao, Pisco, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Chilean Fjords, Punta Arenas, Ushuaia, Cape Horn, Port Stanley, Montevideo and Buenos Aires.
How many days are spent at sea?
13 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Fort Lauderdale, Florida and ends in Buenos Aires.
How long is this cruise?
31 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 18 Nov 2026. A NestCruise advisor can confirm current availability.