

Cruise itinerary
28-Night Europe Cruise from Barcelona
28 nights · Europe · 16 ports of call
28-night Europe cruise aboard Oosterdam, departing Barcelona and calling at Valletta, Khania, Santorini, Kusadasi, Piraeus and Alexandria and 9 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oosterdam
- Cruise line
- Holland America Line
- Duration
- 28 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Barcelona
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Barcelona
Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2At sea
- Day3

Valletta
Arrive 08:00 · Depart 17:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day4At sea
- Day5

Khania
Arrive 08:00 · Depart 17:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day6

Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day7

Kusadasi
Arrive 07:00 · Depart 18:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day8

Piraeus
Arrive 07:00 · Depart 16:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day9At sea
- Day10

Alexandria
Arrive 06:00
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day11

Alexandria
Depart 23:59
Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
- Qaitbay Citadel
- Bibliotheca Alexandrina
- Corniche seafront
- Day12At sea
- Day13

Rhodes
Arrive 08:00 · Depart 18:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day14

Mykonos
Arrive 08:00 · Depart 17:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day15

Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day16At sea
- Day17
Solar Eclipse
Arrive 07:00 · Depart 12:00
- Day18

La Goulette
Arrive 08:00 · Depart 18:00
The port of Tunis on the Gulf of Tunis in Tunisia, the usual landing for ships calling at the capital. The ancient ruins of Carthage and the blue-and-white clifftop village of Sidi Bou Saïd lie close by, with the city's great walled medina a short drive away.
- Carthage ruins
- Sidi Bou Saïd
- Tunis medina
- Day19

Valletta
Arrive 12:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day20

Valletta
Depart 23:59
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day21At sea
- Day22

Cagliari
Arrive 08:00 · Depart 17:00
The capital of Sardinia, an Italian port set across hills above the Gulf of the Angels. Its fortified Castello quarter looks down over the harbour, with a long city beach at Poetto and the Roman amphitheatre among its older landmarks.
- Castello quarter
- Poetto Beach
- Roman amphitheatre
- Day23

Palermo
Arrive 08:00 · Depart 17:00
The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
- Cappella Palatina
- Ballarò market
- Monreale mosaics
- Day24

Messina
Arrive 08:00 · Depart 17:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day25At sea
- Day26

Corfu
Arrive 08:00 · Depart 17:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day27

Argostoli
Arrive 07:00 · Depart 16:00
The capital of Kefalonia, the largest of Greece's Ionian Islands. Rebuilt after a 1953 earthquake, the waterfront town curves around a sheltered lagoon and serves as a base for the island's pale-pebble beaches, caves and the white sand of Myrtos.
- Myrtos Beach
- Melissani Cave
- Koutavos lagoon
- Day28

Khania
Arrive 10:00 · Depart 18:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day29

Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 17 Jul 2027
- 24 Jul 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
28-Night Europe Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 28-night Europe cruise calls at Barcelona, Valletta, Khania, Santorini, Kusadasi, Piraeus, Alexandria, Rhodes, Mykonos, Solar Eclipse, La Goulette, Cagliari, Palermo, Messina, Corfu and Argostoli.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Barcelona and ends in Piraeus.
How long is this cruise?
28 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 17 Jul 2027 and 24 Jul 2027. A NestCruise advisor can confirm current availability.