Cruise itinerary
21-Night Europe Cruise from Trieste
21 nights · Europe · 11 ports of call
21-night Europe cruise aboard Oosterdam, departing Trieste and calling at Rijeka, Split, Santorini, Bodrum, Kusadasi and Istanbul and 4 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oosterdam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Trieste
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Trieste
Depart 17:00
A port city in northeast Italy near the Slovenian border, long the seaward gateway of the Austro-Hungarian Empire. Grand Habsburg-era squares open onto the Adriatic, with the seafront Piazza Unità d'Italia and the white Miramare Castle on the bay.
- Piazza Unità d'Italia
- Miramare Castle
- Viennese cafés
- Day2
Rijeka
Arrive 07:00 · Depart 16:00
Croatia's principal seaport, set where a river valley meets the Kvarner Gulf on the northern Adriatic. A working harbour city with a grand Habsburg-era core, it is crowned by the hilltop Trsat Castle and serves as a gateway to the nearby island of Krk.
- Trsat Castle
- Korzo promenade
- Kvarner Gulf
- Day3
Split
Arrive 07:00 · Depart 16:00
A Croatian port on the Dalmatian coast, built quite literally inside the walls of a Roman emperor's retirement palace. Diocletian's Palace still forms the living old town, its cellars and courtyards woven through with cafes, shops and the cathedral.
- Diocletian's Palace
- Riva promenade
- Marjan Hill
- Day4At sea
- Day5
Santorini
Arrive 10:00 · Depart 19:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day6
Bodrum
Arrive 08:00 · Depart 18:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day7
Kusadasi
Arrive 07:00 · Depart 16:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day8
Istanbul
Arrive 12:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day9
Istanbul
Depart 19:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day10At sea
- Day11
Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day12
Náfplion
Arrive 08:00 · Depart 17:00
A harbour town in the Peloponnese, the first capital of modern Greece, set beneath the Palamidi fortress. Its neoclassical old town runs down to the waterfront, with the small Bourtzi castle standing on an islet in the bay.
- Palamidi fortress
- Bourtzi castle
- Old town squares
- Day13At sea
- Day14
Istanbul
Arrive 08:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day15
Istanbul
Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day16At sea
- Day17
Kusadasi
Arrive 08:00 · Depart 17:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day18
Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day19
Rhodes
Arrive 08:00 · Depart 23:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day20At sea
- Day21
Khania
Arrive 07:00 · Depart 17:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day22
Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 23 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Trieste FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Trieste, Rijeka, Split, Santorini, Bodrum, Kusadasi, Istanbul, Piraeus, Náfplion, Rhodes and Khania.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Trieste and ends in Piraeus.
How long is this cruise?
21 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 23 Sep 2026. A NestCruise advisor can confirm current availability.