Cruise itinerary
21-Night Europe Cruise from Piraeus
21 nights · Europe · 17 ports of call
21-night Europe cruise aboard Oosterdam, departing Piraeus and calling at Scenic Cruising, Kotor, Corfu, Stromboli, Messina and Naples and 10 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oosterdam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Piraeus
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2At sea
- Day3
Scenic Cruising
Kotor
Arrive 08:00 · Depart 17:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day4
Corfu
Arrive 08:00 · Depart 17:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day5
Stromboli
Messina
Arrive 11:00 · Depart 18:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day6
Naples
Arrive 08:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day7
Naples
Depart 17:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day8
Civitavecchia
Arrive 07:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day9
Livorno
Arrive 07:00 · Depart 19:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day10
Portofino
Arrive 07:00 · Depart 17:00
A small fishing village on the Italian Riviera, its pastel houses curved around a sheltered harbour on a wooded promontory in Liguria. Long a retreat for yachts and writers, it has a tiny piazzetta, hillside church and coastal paths toward Genoa.
- Piazzetta harbour
- Castello Brown
- San Fruttuoso
- Day11
Marseille
Arrive 07:00 · Depart 18:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day12At sea
- Day13
Gibraltar
Arrive 12:00 · Depart 19:00
A British territory at the southern tip of Spain, dominated by its towering limestone Rock. Cable cars climb to the summit, home to Europe's only wild monkeys, with sweeping views across the strait toward the coast of Africa.
- The Rock
- Barbary macaques
- St. Michael's Cave
- Day14At sea
- Day15
Barcelona
Arrive 07:00 · Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day16At sea
- Day17
Valletta
Arrive 08:00 · Depart 17:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day18At sea
- Day19
Khania
Arrive 08:00 · Depart 17:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day20
Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day21
Kusadasi
Arrive 07:00 · Depart 18:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day22
Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 12 Jun 2027
- 3 Jul 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Piraeus, Scenic Cruising, Kotor, Corfu, Stromboli, Messina, Naples, Civitavecchia, Livorno, Portofino, Marseille, Gibraltar, Barcelona, Valletta, Khania, Santorini and Kusadasi.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Piraeus.
How long is this cruise?
21 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 12 Jun 2027 and 3 Jul 2027. A NestCruise advisor can confirm current availability.