Oosterdam — 21-Night Europe Cruise from Piraeus

Cruise itinerary

21-Night Europe Cruise from Piraeus

21 nights · Europe · 13 ports of call

21-night Europe cruise aboard Oosterdam, departing Piraeus and calling at Alexandria, Rhodes, Mykonos, Solar Eclipse, La Goulette and Valletta and 6 more.

Free advisor
No booking fees
10,000+ sailings

Narrow your sailing dates See the day-by-day

At a glance

Ship: Oosterdam
Cruise line: Holland America Line
Duration: 21 nights
Region: Europe · Southern Europe · Mediterranean
Departs: Piraeus
Returns: Piraeus

How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.

Where this voyage takes you

Voyage route — calls shown in order; map is schematic.

Day-by-day itinerary

Day
1
- Piraeus
  Depart 16:00
  The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
  - Gateway to Athens
  - Acropolis
  - Aegean ferries
Day
2
At sea
Day
3
- Alexandria
  Arrive 06:00
  Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
  - Qaitbay Citadel
  - Bibliotheca Alexandrina
  - Corniche seafront
Day
4
- Alexandria
  Depart 23:59
  Egypt's great Mediterranean port, founded by Alexander the Great. Once home to the ancient Lighthouse and Library, it keeps a long seafront corniche, the Qaitbay citadel on the old harbour and the modern Bibliotheca Alexandrina library.
  - Qaitbay Citadel
  - Bibliotheca Alexandrina
  - Corniche seafront
Day
5
At sea
Day
6
- Rhodes
  Arrive 08:00 · Depart 18:00
  The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
  - Medieval Old Town
  - Palace of the Grand Master
  - Lindos Acropolis
Day
7
- Mykonos
  Arrive 08:00 · Depart 17:00
  A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
  - Windmills
  - Little Venice
  - Chora town
Day
8
- Piraeus
  Arrive 07:00 · Depart 17:00
  The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
  - Gateway to Athens
  - Acropolis
  - Aegean ferries
Day
9
At sea
Day
10
- Solar Eclipse
  Arrive 07:00 · Depart 12:00
Day
11
- La Goulette
  Arrive 08:00 · Depart 18:00
  The port of Tunis on the Gulf of Tunis in Tunisia, the usual landing for ships calling at the capital. The ancient ruins of Carthage and the blue-and-white clifftop village of Sidi Bou Saïd lie close by, with the city's great walled medina a short drive away.
  - Carthage ruins
  - Sidi Bou Saïd
  - Tunis medina
Day
12
- Valletta
  Arrive 12:00
  Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
  - Grand Harbour
  - St. John's Co-Cathedral
  - Upper Barrakka Gardens
Day
13
- Valletta
  Depart 23:59
  Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
  - Grand Harbour
  - St. John's Co-Cathedral
  - Upper Barrakka Gardens
Day
14
At sea
Day
15
- Cagliari
  Arrive 08:00 · Depart 17:00
  The capital of Sardinia, an Italian port set across hills above the Gulf of the Angels. Its fortified Castello quarter looks down over the harbour, with a long city beach at Poetto and the Roman amphitheatre among its older landmarks.
  - Castello quarter
  - Poetto Beach
  - Roman amphitheatre
Day
16
- Palermo
  Arrive 08:00 · Depart 17:00
  The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
  - Cappella Palatina
  - Ballarò market
  - Monreale mosaics
Day
17
- Messina
  Arrive 08:00 · Depart 17:00
  A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
  - Etna day trips
  - Taormina gateway
  - Astronomical clock
Day
18
At sea
Day
19
- Corfu
  Arrive 08:00 · Depart 17:00
  An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
  - Old Fortress
  - Liston arcade
  - Ionian coves
Day
20
- Argostoli
  Arrive 07:00 · Depart 16:00
  The capital of Kefalonia, the largest of Greece's Ionian Islands. Rebuilt after a 1953 earthquake, the waterfront town curves around a sheltered lagoon and serves as a base for the island's pale-pebble beaches, caves and the white sand of Myrtos.
  - Myrtos Beach
  - Melissani Cave
  - Koutavos lagoon
Day
21
- Khania
  Arrive 10:00 · Depart 18:00
  A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
  - Venetian harbour
  - Balos lagoon
  - Elafonisi beach
Day
22
- Piraeus
  Arrive 07:00
  The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
  - Gateway to Athens
  - Acropolis
  - Aegean ferries

Upcoming departures

24 Jul 2027

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

21-Night Europe Cruise from Piraeus FAQ

Which ports does this cruise visit?

This 21-night Europe cruise calls at Piraeus, Alexandria, Rhodes, Mykonos, Solar Eclipse, La Goulette, Valletta, Cagliari, Palermo, Messina, Corfu, Argostoli and Khania.

How many days are spent at sea?

5 days are spent at sea; the rest are in port.

Where does this cruise depart from?

It is a round-trip sailing from Piraeus.

How long is this cruise?

21 nights aboard Oosterdam.

When does this itinerary sail?

Upcoming departures include 24 Jul 2027. A NestCruise advisor can confirm current availability.

settle in, sail beyond.

Narrow your Oosterdam sailing

Tell us your group and timing — your advisor narrows the cabins and dates that fit and confirms a live fare. No booking fees.

About: Oosterdam — 21-Night Europe Cruise from Piraeus

Your name *Email *

Phone *

Preferred contact

Preferred departure (optional)

Who’s travelling

Adults

18+

Children

2–17 years

Infants

6–23 months

Occasion (optional)Budget (optional)

Anything else? (optional)

Savings opportunities

Optional — tell your advisor what applies and they’ll find every discount you qualify for.

Country of residenceState

Active, reserve, retired, or veteran militaryI'm a Mariner Society member

NestCruise

By checking this box, you agree to receive recurring informational and customer-care text messages from NestCruise at the mobile number you provide — quote updates, booking confirmations, payment reminders, itinerary and document reminders, travel-day service notices, and support replies. Message frequency varies. Message and data rates may apply. Reply STOP to opt out, HELP for help.

By checking this box, I accept the NestCruise Terms of Service and Privacy Policy.

Consent is not a condition of purchase. See our SMS Terms.

No booking fees. Your details are used only to prepare your quote.