Cruise itinerary
21-Night Europe Cruise from Barcelona
21 nights · Europe · 18 ports of call
21-night Europe cruise aboard Oosterdam, departing Barcelona and calling at Marseille, Livorno, Civitavecchia, Naples, Corfu and Dubrovnik and 11 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oosterdam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Barcelona
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Barcelona
Depart 16:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2
Marseille
Arrive 07:00 · Depart 16:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day3
Livorno
Arrive 08:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day4
Civitavecchia
Arrive 07:00 · Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day5
Naples
Arrive 08:00 · Depart 18:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day6At sea
- Day7
Corfu
Arrive 08:00 · Depart 17:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day8
Dubrovnik
Arrive 08:00 · Depart 21:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day9
Scenic Cruising
Kotor
Arrive 08:00 · Depart 15:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day10
Zadar
Arrive 10:00 · Depart 19:00
A walled Adriatic city on Croatia's Dalmatian coast, built on a compact peninsula of Roman and Venetian stone. Zadar is known for its waterfront Sea Organ, the solar Greeting to the Sun installation, and Roman ruins at the old forum.
- Sea Organ
- Roman Forum
- Greeting to the Sun
- Day11
Trieste
Arrive 07:00
A port city in northeast Italy near the Slovenian border, long the seaward gateway of the Austro-Hungarian Empire. Grand Habsburg-era squares open onto the Adriatic, with the seafront Piazza Unità d'Italia and the white Miramare Castle on the bay.
- Piazza Unità d'Italia
- Miramare Castle
- Viennese cafés
- Day12
Trieste
Depart 17:00
A port city in northeast Italy near the Slovenian border, long the seaward gateway of the Austro-Hungarian Empire. Grand Habsburg-era squares open onto the Adriatic, with the seafront Piazza Unità d'Italia and the white Miramare Castle on the bay.
- Piazza Unità d'Italia
- Miramare Castle
- Viennese cafés
- Day13
Rijeka
Arrive 07:00 · Depart 16:00
Croatia's principal seaport, set where a river valley meets the Kvarner Gulf on the northern Adriatic. A working harbour city with a grand Habsburg-era core, it is crowned by the hilltop Trsat Castle and serves as a gateway to the nearby island of Krk.
- Trsat Castle
- Korzo promenade
- Kvarner Gulf
- Day14
Split
Arrive 07:00 · Depart 16:00
A Croatian port on the Dalmatian coast, built quite literally inside the walls of a Roman emperor's retirement palace. Diocletian's Palace still forms the living old town, its cellars and courtyards woven through with cafes, shops and the cathedral.
- Diocletian's Palace
- Riva promenade
- Marjan Hill
- Day15At sea
- Day16
Santorini
Arrive 10:00 · Depart 19:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day17
Bodrum
Arrive 08:00 · Depart 18:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day18
Kusadasi
Arrive 07:00 · Depart 16:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day19
Istanbul
Arrive 12:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day20
Istanbul
Depart 19:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day21At sea
- Day22
Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 12 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Barcelona, Marseille, Livorno, Civitavecchia, Naples, Corfu, Dubrovnik, Scenic Cruising, Kotor, Zadar, Trieste, Rijeka, Split, Santorini, Bodrum, Kusadasi, Istanbul and Piraeus.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Barcelona and ends in Piraeus.
How long is this cruise?
21 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 12 Sep 2026. A NestCruise advisor can confirm current availability.