Cruise itinerary
16-Night Americas Cruise from Fort Lauderdale, Florida
16 nights · Americas · 9 ports of call
16-night Americas cruise aboard Oosterdam, departing Fort Lauderdale, Florida and calling at Grand Cayman, Fuerte Amador, Manta, Salaverry, Callao and General San Martin and 2 more.
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At a glance
- Ship
- Oosterdam
- Cruise line
- Holland America Line
- Duration
- 16 nights
- Region
- Americas · South America
- Departs
- Fort Lauderdale, Florida
- Returns
- San Antonio
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oosterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Fort Lauderdale, Florida
Depart 17:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day2At sea
- Day3
Grand Cayman
Arrive 10:00 · Depart 18:00
The largest of the Cayman Islands, a low coral island in the western Caribbean and a noted diving and offshore-banking centre. George Town's cruise harbour sits a short ride from Seven Mile Beach and the shallow sandbar of Stingray City.
- Seven Mile Beach
- Stingray City
- George Town
- Day4At sea
- Day5
Fuerte Amador
Arrive 21:00
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day6
Fuerte Amador
Depart 16:00
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day7At sea
- Day8
Manta
Arrive 06:00 · Depart 20:00
- Day9At sea
- Day10
Salaverry
Arrive 08:00 · Depart 17:00
- Day11
Callao
Arrive 10:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day12
Callao
Depart 18:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day13
General San Martin
Arrive 07:00 · Depart 18:00
- Day14At sea
- Day15At sea
- Day16
Coquimbo
Arrive 08:00 · Depart 16:00
- Day17
San Antonio
Arrive 07:00
Upcoming departures
- 18 Nov 2026
- 24 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
16-Night Americas Cruise from Fort Lauderdale, Florida FAQ
Which ports does this cruise visit?
This 16-night Americas cruise calls at Fort Lauderdale, Florida, Grand Cayman, Fuerte Amador, Manta, Salaverry, Callao, General San Martin, Coquimbo and San Antonio.
How many days are spent at sea?
6 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Fort Lauderdale, Florida and ends in San Antonio.
How long is this cruise?
16 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 18 Nov 2026 and 24 Mar 2027. A NestCruise advisor can confirm current availability.