

Cruise itinerary
21-Night Europe Cruise from Civitavecchia
21 nights · Europe · 15 ports of call
21-night Europe cruise aboard Nieuw Statendam, departing Civitavecchia and calling at Livorno, Genoa, Marseille, Gibraltar, Barcelona and Alicante and 8 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Nieuw Statendam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Civitavecchia
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Nieuw Statendam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Civitavecchia
Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2

Livorno
Arrive 07:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day3

Genoa
Arrive 07:00 · Depart 16:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day4

Marseille
Arrive 08:00 · Depart 18:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day5At sea
- Day6

Gibraltar
Arrive 12:00 · Depart 19:00
A British territory at the southern tip of Spain, dominated by its towering limestone Rock. Cable cars climb to the summit, home to Europe's only wild monkeys, with sweeping views across the strait toward the coast of Africa.
- The Rock
- Barbary macaques
- St. Michael's Cave
- Day7At sea
- Day8

Barcelona
Arrive 07:00 · Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day9

Alicante
Arrive 08:00 · Depart 17:00
A sun-warmed port on Spain's Costa Blanca, set below the Santa Bárbara castle on its rocky headland. The palm-lined Explanada promenade leads to a long city beach, with the old Barrio Santa Cruz climbing the hill in white houses.
- Santa Bárbara Castle
- Explanada promenade
- Postiguet Beach
- Day10At sea
- Day11

La Goulette
Arrive 08:00 · Depart 17:00
The port of Tunis on the Gulf of Tunis in Tunisia, the usual landing for ships calling at the capital. The ancient ruins of Carthage and the blue-and-white clifftop village of Sidi Bou Saïd lie close by, with the city's great walled medina a short drive away.
- Carthage ruins
- Sidi Bou Saïd
- Tunis medina
- Day12

Valletta
Arrive 09:00 · Depart 20:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day13At sea
- Day14

Khania
Arrive 08:00 · Depart 17:00
A harbour town on the northwest coast of Crete, in Greece, wrapped around a Venetian port. A waterfront lighthouse marks the old harbour mouth, and the pink-sand lagoon of Balos and the beach at Elafonisi lie along the coast to the west.
- Venetian harbour
- Balos lagoon
- Elafonisi beach
- Day15

Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day16

Piraeus
Depart 18:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day17

Santorini
Arrive 08:00 · Depart 17:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day18

Bodrum
Arrive 08:00 · Depart 20:00
A resort town on Turkey's southwest Aegean coast, set on a twin bay beneath the Castle of St. Peter, built by the Knights of St. John. The site of the ancient Mausoleum at Halicarnassus, it is now known for its marina, whitewashed lanes, and nightlife.
- Bodrum Castle
- Mausoleum ruins
- Marina waterfront
- Day19

Rhodes
Arrive 08:00 · Depart 17:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day20

Kusadasi
Arrive 08:00 · Depart 21:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day21At sea
- Day22

Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 19 Feb 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Civitavecchia, Livorno, Genoa, Marseille, Gibraltar, Barcelona, Alicante, La Goulette, Valletta, Khania, Piraeus, Santorini, Bodrum, Rhodes and Kusadasi.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Piraeus.
How long is this cruise?
21 nights aboard Nieuw Statendam.
When does this itinerary sail?
Upcoming departures include 19 Feb 2028. A NestCruise advisor can confirm current availability.